Intracellular potassium and chloride channels: An update

• Autorzy: Debska G. , Kicinska A. , Skalska J. , Szewczyk A.
• Języki publikacji: EN

Abstrakty

EN

Channels selective for potassium or chloride ions are present in all intracellular mem­branes such as mitochondrial membranes, sarcoplasmic/endoplasmic reticulum, nuclear membrane and chromaffin granule membranes. They probably play an important role in events such as acidification of intracellular compartments and regulation of organelle vol­ume. Additionally, intracellular ion channels are targets for pharmacologically active compounds, e.g. mitochondrial potassium channels interact with potassium channel open­ers such as diazoxide. This review describes current observations concerning the proper­ties and functional roles of intracellular potassium and chloride channels.

Słowa kluczowe

EN

chromaffin granule; intracellular membrane; mitochondrion; membrane; potassium channel; ion channel; chloride channel

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2001
• Tom: 48
• Numer: 1
• Opis fizyczny: p.137-144,fig.

Twórcy

autor

Debska G.

• Nencki Institute of Experimental Biology, L.Pasteura 3, 02-096 Warsaw, Poland

autor

Kicinska A.

autor

Skalska J.

autor

Szewczyk A.

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