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2003 | 12 | 5 |

Tytuł artykułu

Effect of nickel [II] chloride oral exposure on urinary nickel excretion and some other elements

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Male Wistar rats were given nickel (II) chloride (NiCl2 • 6 H2O) with drinking water (300 or 1200 ppm Ni for 90 days). Urine volume and nickel, zinc, copper, calcium and inorganic phosphorus were measured in 24 h urine after 45 and 90 days of exposure. The results demonstrate that relatively low-level oral ex­posure (300 ppm Ni) induces an increase of urinary Ni excretion (p < 0.001), but no significant changes in other elements. The higher Ni dose (1200 ppm) caused elevation of this metal in urine (p < 0.001), as well as significant changes of urinary volume, and zinc, copper and inorganic phosphorus concentration.

Wydawca

-

Rocznik

Tom

12

Numer

5

Opis fizyczny

p.563-566

Twórcy

autor
  • Institute of Maritime and Tropical Medicine, Powstania Styczniowego 9b, 81-519 Gdynia, Poland
autor

Bibliografia

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  • 15. CEMPEL M., JANICKA K., WINNICKAA., SMOLIŃSKA D. Effect of nickel chloride on rats after oral administration. Part II. Urinary nickel excretion and some biochemical con­stituents. Acta Pol.Toxicol. 7, 171, 1999.
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  • 17. TOMASZEWSKI J.J. Diagnostyka Laboratoryjna. Wydawnictwo Lekarskie PZWL, Warszawa, 1997.
  • 18. CEMPEL M., JANICKA K. Distribution of nickel, zinc and copper in rats organs after oral administration of nickel (II) chloride. Biol. Trace Elem. Res.(in press).
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-993d0863-78fb-408e-9bc3-b23c8b349df7
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