EN
The aim of this work was to study clinical changes and microorganisms in mouths of three patient groups: with congenital disorders (Cd), dialyzed (D) and control (C). Fifty five patients, 20 to 62 years old were assessed. Swabs and samples of periodontal tissue were used for microscopical study to detect of protozoans and for bacterial and fungal cultures. E. Gingivalis and T. tenax were found in all groups. Three out of Cd patients were infected with Acanthamoeba sp. Fecal bacteria were more often found in D than Cd. In all 30-40 years old D patients, fecal bacteria and various strains of C. albicans occurred. We found that systemie diseases favour instabilities in mouths changing interrelations between protozoa, bacteria and fungi. It may increase risk of clinical complications.