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2007 | 63 | 03 |
Tytuł artykułu

Wplyw deksametazonu na wybrane steroidy plciowe i biochemiczne wskazniki w nasieniu ogierow po podaniu LPS

Autorzy
Warianty tytułu
EN
Effect of dexamethasone on some sex steroids and biochemical parameters in stallion semen following LPS administration
Języki publikacji
PL
Abstrakty
EN
The aim of the study was to determine the effect of dexamethasone injections on changes in seminal plasma testosterone and oestradiol-17b concentration and biochemical characteristics in stallions following endotoxin administration. Three clinically healthy stallions were infused intravenously with endotoxin (LPS) from Escherichia coli 055:B5 at a dose of 0.3 mg/kg b.w.; while four stallions were treated with dexamethasone (0.069 mg/kg b.w., IM) 10 min before the administration of LPS. Endotoxin administration elicited (24h-9 weeks after LPS administration) a significant (P < 0.05) decrease in seminal plasma testosterone (T) and an increase in oestradiol-17β E₂β concentration. Administering endotoxin also influenced the seminal plasma biochemical components including total protein (TPR), albumin (ALB), total cholesterol (CHOL) concentration, and aspartate aminotransferase (AST) activity. A significant (P < 0.05) increase in TPR, ALB, and AST was noted. Dexamethason administration (DEX) had a different effect on endotoxin and induced testosterone and oestradiol-17β changes in the seminal plasma and biochemical quality of the stallion’s semen. DEX treatment had no influence on T, E₂β. The positive influence of DEX was noticed in TPR and AST. The negative influence of administering LPS+DEX in the group of stallions which only received LPS was noted particularly in ALB and CHOL.
Wydawca
-
Rocznik
Tom
63
Numer
03
Opis fizyczny
s.348-352,rys.,bibliogr.
Twórcy
autor
  • Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy w Pulawach, Oddzial w Bydgoszczy, al.Powstancow Wlkp. 10, 85-090 Bydgoszcz
Bibliografia
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Typ dokumentu
Bibliografia
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