PL
Dokonano oceny porównawczej toksyczności 1,5 i 2,0% roztworów wodnych sporządzonych z produktu technicznego zawierającego 59,4% fenylofenolanu sodowego.
EN
Functional accumulation coefficients for 1.5% and 2.0% aqueous solutions of commercial sodium phenylphenolate (used for wood impregnation) were determined on male Wistar rats by the Lim method. Hematological and histopathological examinations were also performed. The cumulative median lethal volumes for the 1.5% and 2.0% solutions determined in our experiment were 98.7 cm3/kg/d and 76.0 cm3/kg/d, respectively. The calculated cumulative coefficients (Kk 1.5% 0.55; Kk2.0% 0,75) and degree of accumulation (Sk 1.5% 181%; Sk 2.0% 126%) point to the cumulative properties of the examined solutions. The symptoms of poisoning: changes in body weight increase and foodstuff intake; morphological changes of spleen and upper airways mucosa; shifts in white blood cell composition observed in our experiment support the toxic and cumulative character of the examined solutions.