Tetrasubstituted purines as inhibitors of CDK1

• Autorzy: Moravec J , Havlicek L. , Moravcova D. , Hanus J. , Fuksova K. , Otyepka M. , Krystof V. , Strnad M.
• Języki publikacji: EN

Słowa kluczowe

EN

cell cycle; cyclin-dependent kinase; regulation; anticancer agent; cell division; purine

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2003
• Tom: 08
• Numer: 2A
• Opis fizyczny: p.596-597

Twórcy

autor

Moravec J

• Institute of Experimental Botany, AS CR, 14220 Prague, Czech Republic

autor

Havlicek L.

autor

Moravcova D.

autor

Hanus J.

autor

Fuksova K.

autor

Otyepka M.

autor

Krystof V.

autor

Strnad M.

Bibliografia

• 1. Roelen, H., Veldman, N., Spek, A.L., Von Frijtag Drabbe Kunzel, J., Mathot, R.A.A. and Ijzerman, A.P. N6,C8-distributed adenosine derivatives as partial agonists for adenosine A1 receptors. J. Med. Chem. 39 (1996) 1463-1471.
• 2. Holmes, R.E. and Robins, R.K. Purine Nucleosides. VII. Direct bromination of adenosine, deoxyadenosine, guanosine, and related purine nucleosides J. Am. Chem. Soc. 86 (1964) 1242- 1245.
• 3. Jones, J.W. and Robins, R.K. Potential purine antagonists. XXIV. The preparation and reactions of some 8-diazopurines. J. Am. Chem. Soc. 82 (1960) 3773-3779.
• 4. Veselý, J., Havlíček, L., Strnad, M., Blow, J.J., Donella-Deana, A., Pinna, L., Letham, D.S., Kato, J., Detivaud, L., Leclerc, S. and Meijer, L. Inhibition of cyclin-dependent kinases by purine derivatives. Eur. J. Biochem. 224 (1994) 771-786.
• 5. Havlíček, L., Hanuš, J., Veselý, J., Leclerc, S., Meijer, L., Shaw, G. and Strnad, M. Cytokinin-derived cyclin-dependent kinase inhibitors: Synthesis and cdc2 inhibitory activity olomoucine and related compounds. J. Med. Chem. 40 (1997) 408-412.
• 6. Otyepka, M., Kryštof, V., Havlíček, L., Siglerová, V., Strnad, M. and Koča, J. Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2. J. Med. Chem. 43 (2000) 2506-2513.