Isolation of the cDNAs encoding secreted and membrane binding proteins from egg of Schistosoma japonicum [Chinese strain]

• Autorzy: Yu C , Zhang F. , Yin X. , Kikuchi M. , Hirayama K.
• Języki publikacji: EN

Abstrakty

EN

The granulomatous reaction which occurs around egg trapped in the intrahepatic venules ultimately may lead to fibrosis, which is the main pathogenesis of schistosomiasis. The excreted proteins from eggs play an important role during this process, and they may be a target for developing new strategies to control the hepatic pathogenesis caused by schistosome infection. In this study, fifteen genes encoding secreted or membrane binding protein were identified with the signal sequence trapping method by retrovirus mediated expression screening (SST-REX) of cDNAs from the egg of Schistosoma japonicum (Chinese strain).

Słowa kluczowe

EN

isolation; granulomatous reaction; membrane; signal sequence trapping; pathogenesis; egg; Chinese strain; binding protein; cDNA; Schistosoma japonicum; schistosomiasis

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 2008
• Tom: 53
• Numer: 1
• Opis fizyczny: p.110-114,fig.,ref.

Twórcy

autor

Yu C

• Jiangsu Institute of Parasitic Diseases, 117 Yangxiang, Meiyuan, 214064, Wuxi, Jiangsu Province, China

autor

Zhang F.

autor

Yin X.

autor

Kikuchi M.

autor

Hirayama K.

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