Basing on the results of model studies, a dynamics of fluoride-phosphate exchange on the styrene-divinyl benzene column, was investigated. Mixtures of F- and PO43- ions in molar ratios of 1:1, 3:2, 2:1, and 3:1, were used. In all experiments a satisfactory ions, separation was achieved with much improved exchange of phosphate ions. Molar ratio of ions had no influence on the course of ion exchange. Fluoride ions were found not to displace bounded phosphate ions but to enter the micropores of filling polymer being adsorbed on its surface.