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2008 | 52 | 3 |

Tytuł artykułu

Topical retinoic acid in the treatment of feline tail gland hyperplasia [stud.tail]: a prospective clinical trial

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The purpose of this prospective, double-blinded, and placebo-controlled clinical trial was to investigate the efficacy of topical cream, containing 0.1% retinoic acid for the treatment of tail gland hyperplasia in cats. Nineteen privately owned cats diagnosed with tail gland hyperplasia, based on history and clinical findings were randomly assigned to either a placebo or an active ingredient treatment group. Clinical evaluations were done by the same investigator, who scored clinical healing, at the beginning, during, and at the end of the treatment. Both owners and investigators were blinded to the allocation to the groups. It was demonstrated that retinoic acid gel treatment significantly decreased (P<0.05) the investigator's clinical scores while no significant changes were detected in the placebo treatment group. In conclusion, treatment with 0.1% retinoic acid cream was effective for the topical management of tail gland hyperplasia in the cats included in the study.

Wydawca

-

Rocznik

Tom

52

Numer

3

Opis fizyczny

p.457-459,fig.,ref.

Twórcy

autor
  • Ministry of Agriculture and Rural Affairs, 06440 Ankara, Turkey
autor
autor
autor

Bibliografia

  • 1. Burton C.S., Sawchuk W.S.: Premature sebaceous gland hyperplasia: successful treatment with isotretinoin. J Am Acad Dermatol 1985, 12, 182-184.
  • 2. Evans A.G., Madewell B.R., Stannard A.A.: A trial of 13-cis-retinoic acid for treatment of squamous cell carcinoma and preneoplastic lesions of the head in cats. Am J Vet Res 1985, 46, 2553-2557.
  • 3. Kaufmann R., Vranes M., Landes E.: Diffuse (presenile) hyperplasia of the sebaceous glands, a new entity? Successful treatment with 13-cis-retinoic acid. Hautarzt 1987, 38, 31-35.
  • 4. Kalinbacak A., Guzel M., Atalay O.: Stud tail in an Ankara cat. J Turk Vet Surg 2002, 8, 91.
  • 5. Landthaler M., Kummermehr J., Wagner A., Plewig G.: Inhibitory effects of 13-cis-retinoic acid on human sebaceous glands. Arch Dermatol Res 1980, 269, 297- 309.
  • 6. Scott D.W., Miller W.H., Griffin C.E.: Keratinization defects. In: Small Animal Dermatology. W.B. Saunders Company, Philadelphia, 1995, pp. 839-840.
  • 7. Strauss J.S., Stewart M.E., Downing D.T.: The effect of 13-cis-retinoic acid on sebaceous glands. Arch Dermatol 1987, 123, 1538-1541.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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