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2008 | 64 | 02 |

Tytuł artykułu

Udzial hemolizy w rozwoju zaburzen nerek i watroby u psow z babeszjoza

Autorzy

Warianty tytułu

EN
Contribution of haemolysis to kidney and liver disturbances in dogs with babesiosis

Języki publikacji

PL

Abstrakty

EN
The aim of the study was to evaluate the influence of natural haemolysis on the state of kidneys and livers in dogs suffering from babesiosis. Two groups of dogs were used in the study - 75 dogs with babesiosis and 20 healthy dogs as the control group. Besides evaluating the health status, direct and indirect laboratory diagnostics were performed: haemolysis and anemia intensification degree by erythrocytes mean count, haematocrite, hemoglobin blood, serum and urine concentration and kidney and liver state by urea, creatinine and bilirubin mean serum concentration, and serum activity of alanine transaminase. Dogs with babesiosis showed various clinical signs of the disease as well as consistent intravascular haemolysis, but of different intensity and rarely causing anemia. The study indicated, above all, the varied effect of hemoglobin and its metabolites released by haemolysis on the development of kidney and liver alterations, which, in turn, depended on the disease pattern and metabolic state of the animal.

Wydawca

-

Rocznik

Tom

64

Numer

02

Opis fizyczny

s.213-218,rys.,tab.,bibliogr.

Twórcy

autor
  • Akademia Rolnicza w Lublinie, ul.Gleboka 30, 20-612 Lublin

Bibliografia

  • 1.Abdullahi S. U., Mohammed A. A., Trimnel A. R., Sannusi A., Alafiatayo R.: Clinical and haematological findings in 70 naturally occurring cases of canine babesiosis. J. Small Anim. Pract. 1990, 31, 145-147.
  • 2.Adachi K., Makimura S.: Changes in anti-erythrocyte membrane antibody level of dogs experimentally infected with Babesia gibsoni. J. Vet. Med. Sci. 1992, 54, 1221-1223.
  • 3.Bordeau P., Gualfi J. F.: Babeszjoza psów. Mag. Wet. 1998, 1, 35-47.
  • 4.Braun J. P., Lefebvre H. P., Watson A. D.: Creatinine in dog: a review. Vet. Clin. Pathol. 2003, 32, 162-179.
  • 5.Camacho A. T., Guitian E. J., Pallas E., Gestall J. J., Olmeda A. S., Goethert H. K., Telford S. R. 3rd, Spielman A.: Azotemia and mortality among Babesia microti - like infected dogs. J. Vet. Intern. Med. 2004, 18, 141-146.
  • 6.Chandoga P., Baranová D., Goldová M., Kozák M., Pálenik L., Skalka J. Jr.: Babesia canis (apicomplexa: piroplasmida), in a siberian husky - a case report. Folia Vet. 2001, 45, 47-50.
  • 7.Conrad P., Thomford J., Yamane I., Whiting J., Bosma L., Uno T., Holshuh H. J., Shelly S.: Hemolytic anemia caused by Babesia gibsoni infection in dogs. J. Am. Med. Assoc. 1991, 199, 601-605.
  • 8.Cotter S. M.: Rozpoznawanie przyczyn niedokrwistości u psów i kotów. Wet. po Dyplomie 2004, 5, 13-22.
  • 9.Ettinger S. J., Feldman E. C.: Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat, Saunders Comp., Philadelphia 2000.
  • 10.Gundłach J. L., Sadzikowski A. B., Tomczuk K.: Babeszjoza psów. Medycyna Wet. 1995, 51, 584-588.
  • 11.Hułas C., Dobrzyński A.: Przypadki babeszjozy psów. Medycyna Wet. 1995, 51, 589-590.
  • 12.Irwin P. J., Hutchinson G. W.: Clinical and pathological findings of Babesia infected dogs. Aust. Vet. J. 1991, 68, 204-209.
  • 13.Jacobson L. S., Clark I. A.: The pathophysiology of canine babesiosis: new approaches to an old puzzle. J. S. Afr. Vet. Assoc. 1994, 65, 134-145.
  • 14.Jacobson L. S., Lobetti R. G., Becker P., Reyers F., Vaughan-Scott T.: Nitric oxide metabolites in naturally occurring canine babesiosis. Vet. Parasitol. 2002, 104, 27-41.
  • 15.Kettner F., Reyers F., Miller D.: Thrombocytopaenia in canine babesiosis and its clinical usefulness. J. S. Afr. Vet. Assoc. 2003, 74, 63-68.
  • 16.Lalick J. J.: The influence of injections homologous hemoglobin on the kidneys of normal and dehydrated animals. J. Exper. Med. 1947, 86, 153-159.
  • 17.Lobetti R. G., Jacobson L. S.: Renal involvement in dog with babesiosis. J. S. Afr. Vet. Assoc. 2001, 72, 23-28.
  • 18.Lobetti R. G., Reyers F.: Met-haemoglobinuria in naturally occurring Babesia canis infection. J. S. Afr. Vet. Assoc. 1996, 67, 88-90.
  • 19.Lobetti R. G., Reyers F., Nesbit J. W.: The comparative role of haemoglobinaemia and hypoxia in the development of canine babesial nephropathy. J. S. Afr. Vet. Assoc. 1996, 67, 188-198.
  • 20.Makinde M. O., Bobade P. A.: Osmotic fragility of erythrocytes in clinically normal dogs and dogs infected with parasites. Res. Vet. Sci. 1994, 57, 343-348.
  • 21.Meinkoth J. H., Kocan A. A., Loud S. D., Lorenz M. D.: Clinical and hematologic effects of experimental infections of dogs with recently identified Babesia gibsoni - like isolates from Oklahoma. J. Am. Med. Assoc. 2002, 220, 185-189.
  • 22.Medaille C., Trumel C., Concordet D., Vergez F., Braun J. P.: Comparison of plasma/serum urea and creatinine concentrations in the dog: a 5-year retrospective study in a commercial veterinary clinical pathology laboratory. J. Vet. Med. A Physiol. Pathol. Clin. Med. 2004, 51, 119-123.
  • 23.Milczak A.: Zaburzenia układu hemostazy w przebiegu babeszjozy psów. Praca doktorska AR, Lublin 2003.
  • 24.Onisihi T., Suzuki S., Horie M., Kajikawa M., Ohishi I., Ejima H.: Serum hemolytic activity of Babesia gibsoni - infected dogs: the difference in activity between self and nonself red blood cells. J. Vet. Med. Sci. 1993, 55, 203-206.
  • 25.Otsuka Y., Yamasaki M., Yamato O., Maede Y.: Increased generation of superoxide in erythrocytes infected with Babesia gibsoni. J. Vet. Sci. 2001, 63, 1077-1081.
  • 26.Pinkiewicz E., Grzebuła S.: Przypadek babeszjozy u psa. Medycyna Wet. 1966, 22, 143-144.
  • 27.Reyers F., Leisewitz A., Lobetti R. G., Milner R. J., Jacobson L. S., van Zyl M.: Canine babesiosis in South Africa: more then one disease. Does this serve as a model for falciparum malaria? Ann. Trop. Med. Parasitol. 1998, 92, 503-511.
  • 28.Ross L. A.: Diagnostyka chorób oraz niewydolność nerek. Mag. Wet. 1995, 4, 300-304.
  • 29.Taylor J. H., Guthrie A. J., Leisewitz A.: The effect of endogenously produced carbon monoxide on the oxygen status of infected with Babesia canis. J. S. Afr. Assoc. 1991, 62, 153-155.
  • 30.Winnicka A.: Wartości referencyjne podstawowych badań laboratoryjnych w weterynarii. Wyd. SGGW, Warszawa 2004.
  • 31.Zager R. A., Gamelin L. M.: Pathogenetic mechanisms in experimental hemoglobinuric acute renal failure. Am. J. Physiol. 1989, 256, 446-455.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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