Determination of octanol-water partition coefficients for long-chain homologs of orcinol from cereal grains

• Autorzy: Kozubek A.
• Języki publikacji: EN

Abstrakty

EN

Polycratic reversed-phase high-performance liquid chromatography (RPHPLC) was used for estimation of the octanol/water partition coefficient for three highly hydrophobic long chain orcinol homologs. The homologs studied (C 15:0, C 17:0 and C 19:0) showed high preference for hydrophobic phase as evidenced by their high octanol/water partition coefficient (log P o/w ) values of 7.02-7.74; 8.71-9.47 and 10.49-11.32 for the 95% prediction interval, respectively. Experimentally estimated values were compared with log P values calculated with the use of several fragmental systems. The experimental values of log P o/w are in best agreement to those calculated with the use of the Klopman system (Klopman, Gv Namboodiri, K. & Schochet, M., 1985, /. Comput. Chem. 6,28-38). The lack of appropriate standard compounds with known log P 0/w in the range over 6 markedly affected the accuracy of experimental determinations.

Słowa kluczowe

EN

orcinol; phenolic lipid; cereal grain; alkylresorcinol; octanol-water partition

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1995
• Tom: 42
• Numer: 2
• Opis fizyczny: p.247-251,fig.

Twórcy

autor

Kozubek A.

• University of Wroclaw, S.Przybyszewskiego 63-77, 51-148 Wroclaw, Poland

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