Infection with Echinococcus granulosus [Batsch, 1786] and expression of superoxide dismutase gene at mRNA level in hepatocytes

• Autorzy: Kozlowska-Loj J , Rzymowska J.
• Języki publikacji: EN

Abstrakty

EN

Superoxide dismutase (SOD) plays an important role in detoxication of the organism. Its function is to protect the organism against the cytotoxic action of free radicals. The highest expression of superoxide dismutase was observed in the hepatocytes adjacent to the hydatid cyst. The expression of this gene in the hepatocytes of infected livers 5 cm apart from the infection site was slightly lower.

Słowa kluczowe

EN

parasitic disease; pig; Echinococcus granulosus; superoxide dismutase; infection; gene expression; mRNA level; animal disease; organism; parasite; detoxication; parasitology; hepatocyte

• Wydawca: -
• Czasopismo: Wiadomości Parazytologiczne
• Rocznik: 2006
• Tom: 52
• Numer: 4
• Opis fizyczny: p.287-289,fig.,ref.

Twórcy

autor

Kozlowska-Loj J

• Skubiszewski Medical University of Lublin, Staszica 6, 20-081 Lublin, Poland

autor

Rzymowska J.

Bibliografia

• [1] Piacenza L., Radi R., Goni F., Carmona C. 1998. CuZn superoxide dismutase activities from Fasciola hepatica. Parasitology 117: 555-562.
• [2] Leid R.W., Suquet C.M. 1986. A superoxide dismutase of metacestodes of Taenia taeniaeformis. Molecular and Biochemical Parasitology 18: 301-311.
• [3] Limbery A.J., Thompson R.C.1988. Electrophoretic analysis of genetic variation in Echinococcus granulosus from domestic hosts in Australia. International Journal for Parasitology 18: 803-811.
• [4] Fridovich I. 1995. Superroxide radical and superoxide dismutases. Annual Review of Biochemistry 64: 97-112.
• [5] Salinas G., Cordozo S. 2000. Echinococcus granulosus: Heterogeneity and differential expression of superoxide dismutases. Experimental Parasitology 94: 56-59.
• [6] Liddell S., Knox D.P. 1998. Extracellular and cytoplasmic CuZn superoxide dismutases from Haemonchus contortus. Parasitology 116: 383-394.
• [7] Rao D.G., Mohiyuddin S. 1974. Incidence of hydatid cyst in bovines and histopathological changes of pulmonary tissue in hydatidosis. Indian Journal of Animal Science 44: 437-440.