EN
The present study was undertaken to examine the effects of immunostimulation with isoprinozine (Isoprivet) on the hygienic quality of milk and the health status of mammary glands. Eight HF cows with mastitis whose milk did not meet the extra- class requirements were involved. The following examinations were performed: clinical examination of the udder, macroscopic assessment of milk secretions, FCR, milk cultures, quantitative determination of microorganisms and somatic cell count. No other preparations were used during the experiment. The preliminary results show that isoprinozine has beneficial therapeutic and prophylactic effects on dairy cows already affected or at risk of mastitis. Moreover, it markedly improves the parameters of hygienic assess- ment of raw milk whose quality is maintained within acceptable standards. The findings suggest that isoprinozine may be used as a stimulator of non-specific mechanisms of immune response during lactation in cows.