Open field stress and neurons containing calcium-binding proteins in the piriform cortex of the rat

• Autorzy: Klejbor I. , Ludkiewicz B. , Domaradzka-Pytel B. , Wojcik S. , Morys J.
• Języki publikacji: EN

Abstrakty

EN

In the present study we wanted to check whether the expression of the c-Fos protein (the marker of cellular activity) appears in cells containing calcium-binding proteins (CaBPs) in animals exposed to the open field test. Eight adult Wistar rats were examined. In the first step the open field test was applied throughout 10 minutes. After perfusional fixation brains were frozen and cut on the cryostat in the coronal plane and stained with the standard immunohistochemical method. Sections were double stained for c-Fos and CaBPs: parvalbumin (PV), calbindin (CB), calretinin (CR). c-Fos positive cells were localized predominantly in layers II and III of the piriform cortex (PC). The double labeling study showed that neurons containing CaBPs are rarely c-Fos-immunoreactive. Often PV-positive and CB-positive fibers surround c-Fos-positive neurons in layers II and III in a form of a basket. It seems that cells containing CaBPs are not directly involved in the response to aversive stimuli but cells containing those calcium-binding proteins might influence directly c-Fos positive neurons of PC.

Słowa kluczowe

EN

calcium binding protein; piriform cortex; c-Fos protein; neuron; rat; open field stress

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology
• Rocznik: 2005
• Tom: 56
• Numer: 2
• Opis fizyczny: p.223-231,fig.,ref.

Twórcy

autor

Klejbor I.

• Medical University of Gdansk, 1 Debinki Street, 80-211 Gdansk, Poland

autor

Ludkiewicz B.

autor

Domaradzka-Pytel B.

autor

Wojcik S.

autor

Morys J.