Detection of a circulating antigen of Toxocara canis in the sera of naturally infected men and experimental animals

• Autorzy: Dzbenski T H , Bitkowska E. , Golab E.
• Języki publikacji: EN

Abstrakty

EN

Circulating antigen of Toxocara canis was demonstrated in the sera of experimentally infected rabbits and in patients suspected of the infection. The antigen appeared in the circulation between days 7-14 post infection in animals infected with 5,000 to 20,000 embryonated eggs of the parasite and on 3rd-4th day in rabbits infected with 50,000 eggs. Afterwards, it was present in the sera at irregular intervals until the end of observation period, either free or in complexes with specific antibodies of the IgG or IgM class. Western-blot analysis of infected sera detected two components of the antigen at approximately 32 and 92 kDa. Detection of the antigen in examined serum samples may aid the diagnosis of toxocaral infection, particularly in cases suspected of unspecific reactions in the tests for antibodies.

Słowa kluczowe

EN

infection; serum; experimental animal; central nervous system; antibody; parasite; larval invasion; antigen; patient; man; heavy infection; toxocariasis; dog; lung; liver; detection; rabbit; Toxocara canis

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1999
• Tom: 44
• Numer: 2
• Opis fizyczny: p.137-141,fig.

Twórcy

autor

Dzbenski T H

• National Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland

autor

Bitkowska E.

autor

Golab E.

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