Aortic bifurcation angle as an independent risk factor for aortoiliac occlusive disease

• Autorzy: Shakeri A B , Tubbs R.S. , Shoja M.M. , Nosratinia H. , Oakes W.J.
• Języki publikacji: EN

Abstrakty

EN

Recently, there has been interest in potential geometric risk factors that might result in or exaggerate atherosclerosis. The aortic bifurcation is a complex anatomical area dividing the high pressure blood of the descending abdominal aorta into the lower limbs and pelvis. The distribution of the bifurcation angle and any asymmetry, its relation with age and its possible contribution to the risk of aortoiliac atherosclerosis are presented here. Statistical analysis was performed by SPSS version 11.0 using, Fisher’s exact test, the Pearson and Spearman correlation tests and logistic regression analysis. The p value was set at 0.05. No correlations were found between age, bifurcation angle and angle asymmetry in the Pearson test (p > 0.05). Logistic regression analysis revealed that the bifurcation angle, but not its asymmetry, gender or age, was a significant and independent risk factor for aortoiliac atherosclerosis (model r² = 0.662, p = 0.027). With additional study these results may have implications regarding risk factors for aortoiliac atherosclerosis. To our knowledge, this study is the first of its kind to indicate the potential of such an important geometric risk factor for atherosclerosis at the aortic bifurcation.

Słowa kluczowe

EN

human disease; risk factor; aortoiliac occlusive disease; anatomy; aortic bifurcation; aorta; artery; atherosclerosis

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2007
• Tom: 66
• Numer: 3
• Opis fizyczny: p.181-184,fig.,ref.

Twórcy

autor

Shakeri A B

• Tabriz University of Medical Sciences, Tabriz, Iran

autor

Tubbs R.S.

autor

Shoja M.M.

autor

Nosratinia H.

autor

Oakes W.J.

Bibliografia

• 1. Bargeron CB, Hutchins GM, Moore GW, Deters OJ, Mark FF, Friedman MH (1986) Distribution of the geometric parameters of human aortic bifurcations. Arteriosclerosis, 6: 109–113.
• 2. Cacoub P, Godeau P (1993) Risk factors for atherosclero-tic aortoiliac occlusive disease. Ann Vasc Surg, 7: 394–405.
• 3. Friedman MH, Baker PB, Ding Z, Kuban BD (1996) Relationship between the geometry and quantitative morphology of the left anterior descending coronary artery. Atherosclerosis, 125: 183–192.
• 4. Friedman FH, Ding Z (1998) Variability of the planarity of the human aortic bifurcation. Med Eng Physics, 20: 469–472.
• 5. Goubergrits L, Affeld K, Fernandez-Britto J, Falcon L (2001) Atherosclerosis in the human common carotid artery. A morphometric study of 31 specimens. Pathol Res Pract, 197: 803–809.
• 6. Raffetto JD, Montgomery JE, Eberhardt RT, LaMorte WW, Menzoian JO (2005) Differences in risk factors for lower extremity arterial occlusive disease. J Am Coll Surg, 20: 918–924.
• 7. Schulz UGR, Rothwell PM (2001) Major variation in carotid bifurcation anatomy: a possible risk factor for plaque development? Stroke, 32: 2522–2529.
• 8. Shah PM, Scarton HA, Tsapogas MJ (1978) Geometric anatomy of the aortic-common iliac bifurcation. J Anat, 126: 451–458.
• 9. Smedby O (1998) Geometrical risk factors for atherosclerosis in the femoral artery: a longitudinal angiographic study. Ann Biomed Eng, 26: 391–397.
• 10. Smedby O (1996) Geometric risk factors for atherosclerosis in the aortic bifurcation: A digitized angiography study. Ann Biomed Eng, 24: 481–488.
• 11. Smith FB, Lee AJ, Fowkes FG, Lowe GD, Rumley A (1996) Variation in cardiovascular risk factors by angiographic site of lower limb atherosclerosis. Eur J Vasc Endovasc Surg, 11: 340–346.
• 12. Sun H, Kuban BD, Schmalbrock P, Friedman MH (1994) Measurement of the geometric parameters of the aortic bifurcation from magnetic resonance images. Ann Biomed Eng, 22: 229–239.