Charakterystyka szczepow Neisseria meningitidis izolowanych od nosicieli

• Autorzy: Grzybowska W. , Tyski S.
• Języki publikacji: PL

Abstrakty

PL

Przedstawiono analizę fenotypową i ocenę lekowrażliwości szczepów N. meningitidis wyizolowanych z jamy nosowo-gardłowej od nosicieli w latach 1998-1999. Dla wybranej grupy izolatów N. meningitidis przeprowadzono również badania genotypowe.

EN

Neisseria meningitidis carriers strains were isolated from 17-19 teenagers (n=14) and recruits (n=267). The longitudinal study comprises three meningococcal carriage trials performed on healthy young men during two - six months of their service in Polish military units. Altogether 54, 124 and 89 meningococcal strains were obtained during spring 1998 and autumn 1998,1999 trials. Sixty two percent of meningococcal carrier strains were non-groupable,however among the remaining strains, serogroup B was predominant (29,5%). During spring 1998 and autumn 1999 trials the predominant phenotypes were N. meningitidis NG:21:P1.7, but during the autumn 1998 NG:21:P1.7 or NG:NT:P1.5. Ribotyping of type 21 and/or subtype P1.7 strains (n=27) showed presence of 2 main ribotypes. Pulsed Field Gel Electrophoresis of consecutive isolates recovered from the same carrier showed great similarity of the patterns.

Słowa kluczowe

PL

Neisseria meningitidis; wrazliwosc na leki; jama nosowo-gardlowa; szczepy bakteryjne; badania genotypowe; analiza fenotypowa; nosicielstwo

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2000
• Tom: 52
• Numer: 3
• Opis fizyczny: s.257-266,rys.,tab.,bibliogr.

Twórcy

autor

Grzybowska W.

• Instytut Lekow, 00-725 Warszawa, ul.Chelmska 30-34

autor

Tyski S.

Bibliografia

• 1. Caugant DA, Kristiansen BE, Froholm LO i inni. Clonal diversity of Neisseria meningitidis, from a population of asymptomatic carriers. Infect Immun 1988; 56: 2060-68.
• 2. Grzybowska W, Tyski S. Aspekty nosicielstwa Neisseria meningitidis w jamie nosowo- gardłowej. Mikrobiologia Medycyna 1998; 3: 38-43.
• 3. Cartwright KAV, Stuart JM, Robinson PM. Meningococcal carriage in close contacts of case. Epidemiol Infect 1991; 106: 133-41.
• 4. Krizova P, Musilek M, Danielova V i inni. New serotype candidate of Neisseria meningitides. Centr Eur J Publ Hlth 1996; 4: 169-72.
• 5. Tzanakaki G, Blackwell CC, Kremastinou J. Serogroups, serotypes and subtypes of Neisseria meningitidis isolated from patients and carriers in Greece. J Med Microbiol 1993; 38:19-22.
• 6. Weis N, Lind I. Pharyngeal carriage of Neisseria meningitidis before and after treatment of meningococcal disease. J Med Microbiol 1994; 41: 339-42.
• 7. Tyski S, Grzybowska W, Lind I. Active surveillance of meningococcal meningitis in Poland. Centr Eur J Publ Hlth 1998; 6: 219-24.
• 8. Grzybowska W, Tyski S, Dulny G i inni. Characterization of Neisseria meningitidis type 22, the predominant invasive strains in Poland. 5th Meeting of European Monitoring Group on Meningococci, Kreta, Grecja, kwiecień 28-30 1999.
• 9. Tyski S, Grzybowska W. Phenotype and genetic analysis of Neisseria meningitidis type 22 strains isolated in Poland. IX International Congress of Bacteriology & Applied Microbiology. Sydney, Australia, sierpień 16-20, 1999.
• 10. Tyski S, Grzybowska W, Dulny G. Badania nosicielstwa Neisseria meningitidis u młodzieży osób dorosłych (poborowych). Med Dośw Mikrobiol 2000; 52: 247-55.
• 11. Kronvall GA. A rapid slide agglutination for typing pneumococci by means of specific antibody adsorption to protein A containing staphylococci. J Med Microbiol 1973; 6:187-89.
• 12. Abdillahi H, Poolman JT. Whole cell ELISA for typing N. meningitidis with monoclonal antibodies. FEMS Microbiological Letters (1987) 48: 367-71.
• 13. Nicolas P, Parzy D, Martel G. Pulsed-Field Gel Electrophoresis analysis of clonal relatioships among Neisseria meningitidis A strains from different outbreaks. Eur J Clin Microbiol Infect Dis 1997; 16: 541-44.
• 14. Bruce J. Automated system rapidly identifies and characterizes microorganisms in food. Food Technology 1996; January: 77-81.
• 15. Andersen J, Berthelsen L, Jensen B i inni. Dynamics of the meningococcal carrier state and characteristics of the carrier strains: a longitudinal study within three cohorts of military recruits. Epidem Infect 1998; 121:85-94.
• 16. Cybulska J, Jeljaszewicz J. Prevalence of serological groups of Neisseria meningitidis and their susceptibility to 31 antimicrobial agents. Zbl Bakt Mikrobiol Hyg 1980; 248: 239-47.