Immunogenicity of Trichophyton mentagrophytes isolated from Arctic foxes with ringworm

• Autorzy: Kostro K.
• Języki publikacji: EN

Abstrakty

EN

Immunogenicity of six strains of Trichophyton mentagrophytes var. granulosum isolated from arctic foxes with ringworm was evaluated in guinea pigs and foxes. Two strains of T. mentagrophytes (Tm-3 and Tm-4) out of six examined (Tm- 1, Tm-2, Tm-3, Tm-4, Tm-5 and Tm-6) induced in the experimental foxes a strong cellular immune response measured by the leukocyte migration inhibition test (LMIT), lymphocyte transformation test (LTT), and by skin delayed-type hypersensitivity (DTH). The guinea pigs immunised with Tm-3 and Tm-4 were well protected against the artificial infection with the virulent strain of T. mentagrophytes (Tm-9). These two strains of T. mentagrophytes with high immunogenic properties were used for production of a vaccine against ringworm in foxes.

Słowa kluczowe

EN

Arctic fox; Trichophyton mentagrophytes; guinea pig; immunogenicity; immune response; fox

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2004
• Tom: 07
• Numer: 1
• Opis fizyczny: p.15-20,fig.,ref.

Twórcy

autor

Kostro K.

• University of Agriculture, Gleboka 30, 20-612 Lublin, Poland