Udzial wirusow TT w klinicznej postaci choroby o etiologii wieloczynnikowej, ze szczegolnym uwzglednieniem swin

• Autorzy: Truszczynski M , Pejsak Z.

Warianty tytułu

EN

Participation of TT viruses in the clinical form of diseases of multifactorial etiology with particular reference to swine

• Języki publikacji: PL

Abstrakty

EN

This article is a review of recently published papers dealing with the possible participation of TT viruses in the multifactorial etiology of disease syndromes, particularly in postweaning multisystemic wasting syndrome (PMWS) of swine. The information concerning the taxonomy of these viruses is presented. The virus strain of this group was demonstrated for the first time in 1997 in a human in Japan and was called TTV in reference to the initials of his name. Recently the International Committee of Taxonomy of Viruses has established a new meaning of TT, namely Torque teno virus, deriving from the Latin terms “torque” meaning “necklace” and “tenuis” meaning “thin”. These terms were chosen to reflect the shape of the TTV genome. TTV was classified to the Anellovirus genus of the Circoviridae family. It was stated that there is no evidence of a link between TTV infection of humans and specific diseases. The same was true in relation to infection of cattle, sheep, chickens, dogs, cats and swine infected by other TTV strains, specific in its replication for a particular species of animals. The following text deals particularly with the last mentioned species. Globally TTV infection is widely spread in pigs. Animals, among them pigs, remain infected and even viremic for years without any apparent negative effects. However, in coinfection with porcine circovirus type 2 (PCV2), being the main etiological factor of PMWS, TTV may possibly contribute to the development of the clinical course of the disease. This is more evident in gnotobiotic pigs. In case of an infection exclusively with TTV in gnotobiotic pigs no clinical symptoms occur. However post mortem pathological changes including thymic atrophy, glomerulonephropathy and modest lymphocytic to histiocytic infiltrates in the liver are found. Summarizing, research concerning the role of TTV in the multifactorial etiology of disease syndromes needs to be continued.

Słowa kluczowe

PL

choroby wieloczynnikowe; czynniki chorobotworcze; wirusy; wirusy TTV; wlasciwosci; wystepowanie; chorobotworczosc; trzoda chlewna; choroby zwierzat

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2010
• Tom: 66
• Numer: 04
• Opis fizyczny: s.219-221,bibliogr.

Twórcy

autor

Truszczynski M

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

autor

Pejsak Z.

Bibliografia

• 1. Allan G. M., Ellis J. A.: Porcine circoviruses: a review. J. Vet. Dian. Incest. 2000, 12, 3-14.
• 2. Allan G. M., Kennedy S., McNeilly F., Foster J. C., Ellis J. A., Krakowka S., Meehan B. M., Adair B. M.: Experimental reproduction of severe wasting disease by co-infection of pigs with porcine circovirus and porcine parvovirus. J. Comp. Pathol. 1999, 121, 1-11.
• 3. Allan G. M., McNeilly F., Ellis J., Krakowka S., Meehan B., McNair I., Walker I., Kennedy S.: Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication. Arch. Virol. 2000, 145, 2421-2429.
• 4. Allan G. M., McNeilly F., Meehan B., Kennedy S., Johnston D., Ellis J., Krakowka S., Fossum C., Wattrang E., Wallgren P.: Reproduction of PMWS with a 1993 Swedish isolated of PCV-2. Vet. Rec. 2002, 150, 255-256.
• 5. Bendinelli M., Pistello M., Maggi F., Fornai C., Frezer G., Vatteroni L.: Molecular properties, biology, and clinical implications of TT virus, a recently identified widespread infectious agent of humans. Clin. Microbiol. Rev. 2001, 14, 98-112.
• 6. Biagini P., Todd D., Bendinelli M., Hino S., Mankertz A., Mishiro S., Niel C., Okamoto H., Raidal S. R., Ritchie B. W.: Anellovirus, [w:] Rauquet C. M., Mayo M. A., Maniloff J., Desselberger U., Ball L. A. (eds), Eight Report of the International Committee on Taxonomy of Viruses. Academic Press, London 2005, 335-341.
• 7. Bigarré L., Beven V., de Boisséson C., Grasland B., Rose N., Biagini P., Jestin A.: Pig anelloviruses are highly prevalent in swine heros in France. J. Gen. Virol. 2005, 85, 631-635.
• 8. Bolin S. R., Stoffregen W. C., Nayar G. P. S., Hamel A. L.: Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrums-deprived piglets with type 2 porcine circovirus. J. Vet. Diagn. Invest. 2001, 13, 185-194.
• 9. Ellis J. A., Allan G., Krakowka S.: Effect of coinfection with genogroup 1 porcine torque teno virus on porcine circovirus type 2-associated postweaning multisystemic wasting syndrome in gnotobiotic pigs. Am. J. Vet. Res. 2008, 69, 1608-1614.
• 10. Kekarainen T., López-Soria S., Segalés J.: Detection of swine Torque teno virus genogroups 1 and 2 in boar sera and semen. Theriogenology 2007, 68, 966-971.
• 11. Kekarainen T., Sibila M., Segalés J.: Prevalence of swine Torque teno virus in post-weaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs in Spain. J. Gen. Virol. 2006, 87, 833-837.
• 12. Krakowka S., Ellis J. A.: Evaluation of the effects of porcine genogroup 1 torque teno virus in gnotobiotic swine. Am. J. Vet. Res. 2008, 69, 1623-1629.
• 13. Krakowka S., Ellis J. A., Meehan B., Kennedy S., McNeilly F., Allan G. A.: Viral wasting syndrome of swine: experimental reproduction of postweaning multisystemic wasting syndrome in gnotobiotic swine by coinfection with porcine circovirus 2 and porcine parvovirus. Vet. Pathol. 2000, 37, 254-263.
• 14. Leary T. P., Erker J. C., Chalmers M. L., Desai S. M., Mushahwar I. K.: Improved detection systems for TT virus reveal high prevalence in humans, non-human primates and farm animals. J. Gen. Virol. 1999, 80, 2115-2120.
• 15. Martelli F., Caprioli A., Di Bartolo I., Cibin V., Pezzotti G., Ruggeri M., Ostanello F.: Detection of swine torque teno virus in Italian pig herds. J. Vet. Med. 2006, B53, 234-238.
• 16. Martínez L., Kekarainen T., Sibila M., Ruiz-Fons F., Vidal D., Gortázar C., Segalés J.: Torque teno virus (TTV) is highly prevalent in the European wild boar (Sus scrofa). Vet. Microbiol. 2006, 118, 223-229.
• 17. McKeown N. E., Fenaux M., Halbur P. G., Meng X. J.: Molecular characterization of porcine TT virus, an orphan virus, in pigs from six different countries. Vet. Microbiol. 2004, 104, 113-117.
• 18. Miyata H., Tsunoda H., Kazi A., Hamada A., Khan M. A., Murakami J., Kamahora T., Shiraki K., Hino S.: Identification of a novel GC-Rich 113-nucleotide region to complete the circular, singlestranded DNA genome of TT virus, the first human circovirus. J. Virology 1999, 73, 3582-3586.
• 19. Niel C., Diniz-Mendes L., Devalle S.: Rolling-circle amplification of Torque teno virus (TTV) complete genomes from human and swine sera and identification of a novel swine TTV genogroup. J. Gen. Virol. 2005, 86, 1343-1347.
• 20. Nishizawa T., Okamoto H., Konishi K., Yoshizawa H., Miyakawa Y., Mayumi M.: A novel DNA virus (TTV) associated with elevated transaminase levels in post-transfusion hepatitis of unknown etiology. Biochem. Biophys. Res. Comm. 1997, 241, 92-97.
• 21. Okamoto H., Nishizawa T., Tawara A., Peng Y., Takahashi M., Kishimoto J., Tanaka T., Miyakawa Y., Mayumi M.: Species-specific TT viruses in humans and nonhuman primates and their phylogenetic relatedness. Virology 2000, 277, 368-378.
• 22. Okamoto H., Takahashi M., Nishizawa T., Tawara A., Fukai K., Muramatsu U., Naito Y., Yoshikawa A.: Genomic characterization of TT virus (TTV) in pigs, cats and dogs and their relatedness with species-specific TTV in primates and tupaias. J. Gen. Virol. 2002, 83, 1291-1297.
• 23. Todd D., Bendinelli M., Biagini P., Hino S., Mankertz A., Mishiro S., Niel C., Okamoto H., Raidal S., Ritchie B. W., Teo C. C.: Virus Taxonomy. VIIIth Report of the International Committee on Taxonomy of Viruses. Academic Press, London 2005, 335-341.
• 24. Truszczyński M., Pejsak Z.: Poodsadzeniowy, wielonarządowy zespół wyniszczający świń. Medycyna Wet. 2007, 63, 499-502.