EN
The studies have been conducted on 40 male mice. The experiment was connected with the influence of B₁, B₂ and B₆ vitamins on some lysosomal enzyme activities in the liver and kidney. The thiamin injection decreased lysosomal esterase, lysosomal lipase and alanine aminopeptidase activities in the liver; the ryboflavin injection - lysosomal esterase and alanine aminopeptidase, and pyridoxine injection - lysosomal esterase, cathepsin D and L and alanine aminopeptidase. Ryboflavin increased the activity of β-glucuronidase, N-acetyl-β-glucosaminidase, acid phosphatase and leucine aminopeptidase in the liver; pyridoxine N-acetyl-β-glucosaminidase and leucine aminopeptidase activity. Thiamin increased β-glucuronidase, β-galactosidase, N-acetyl-β-glucosaminidase, acid phosphatase, lysosomal lipase, cathepsin D and L, leucine aminopeptidase and alanine aminopeptidase activity in the kidney; ryboflavin - β-glucuronidase, β-galactosidase, N-acetyl-β-glucosaminidase, acid phosphatase, lysosomal lipase, cathepsin D and L, leucine aminopeptidase and alanine aminopeptidase activity, while pyridoxine - β-glucuronidase, β-galactosidase, N-acetyl-β-glucosaminidase, acid phosphatase, leucine aminopeptidase and alanine aminopeptidase. Vitamins B₁, B₂ and B₆ only decreased lysosomal esterase activity in the kidney. In comparison with the liver, the kidney revealed the greater reactivity of the studied lysosomal enzymes.