Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice

• Autorzy: Przybojewska B. , Plucienniczak G.
• Języki publikacji: EN

Abstrakty

EN

The c-H-ras-1 gene of an B6C3F1 mouse was isolated and nucleotide sequence determined. Our study has revealed that this c-H-ras-1 gene consists of four exons, separated by three introns ranging in size from 150 to 649 bp. The coding parts of the sequence of mouse c-H-ras-1 gene show no important differences as compared with those of the rat, hamster and human gene. More numerous changes were found in introns. The identity of mouse c-H-ras-1 gene with rat, hamster and human ones at the nucleotide level is 86.40%, 80.04% and 67.87%, respectively. Comparison of amino acids in protein sequence of c-H-ras gene of mouse, rat, hamster and human points to high degree of conservation of the gene.

Słowa kluczowe

EN

gene; mouse; carcinogen; man; mice; animal tumour; amino acid sequence; hamster; oncogene; rat; nucleotide sequence

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1996
• Tom: 43
• Numer: 3
• Opis fizyczny: p.575-578,fig.

Twórcy

autor

Przybojewska B.

• Institute of Occupational Medicine, Teresy 8, Lodz, Poland

autor

Plucienniczak G.

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