Fungistatic properties of glucosinolates - a reconnaissance study

• Autorzy: Goralska K , Dynowska M , Ciska E
• Języki publikacji: EN

Abstrakty

EN

The aim of our study was to investigate fungistatic properties of glucosinolates from seeds of four cruciferous plants against Candida albicans, obtained from different sections of the gastrointestinal and respiratory tracts. The examined extracts were observed to exert different effects on fungi depending on the site of their isolation. The strongest antimycotic activity was reported for the extract obtained from seeds of broccoli – the extract appeared more effective than fluconazole. In contrast, upon the activity of white mustard seeds extract the size of the growth inhibition zone was similar to that yielded by fluconazole. Promising results of our experiments suggest the need to further investigate the field.

Słowa kluczowe

EN

cruciferous plant; seed; glucosinolate; antifungal activity; Candida albicans; vegetable-rich diet

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2009
• Tom: 18
• Numer: 3
• Opis fizyczny: p.377-382,fig.,ref.

Twórcy

autor

Goralska K

• Chair of Mycology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-957 Olsztyn, Poland

autor

Dynowska M

• Chair of Mycology, University of Warmia and Mazury in Olsztyn, Oczapowskiego 1A, 10-957 Olsztyn, Poland

autor

Ciska E

• Department of Food Technology, Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences in Olsztyn, Poland

Bibliografia

• 1. FENWICK G. R., HEANEY R. K., MULLIN W. J. Glucosinolates and their breakdown products in food and food plants. Crit. Rev. Food Sci. Nutr. 18, 123, 1983.
• 2. RABOT S., NUGON-BAUDON L., RAIBAUD P., SZYLIT O. Rapeseed meal toxicity in gnotobiotic rats; influence of a whole human faecal flora or single human strains of Escherichia coli and Bacteroides vulgatus. BR. J.NUTR. 70, 323, 1993.
• 3. NUGON-BAUDON L., RABOT S., WAL J. M., SZYLIT O. Interactions of digestive microflora with glucosinolates in rapeseed meal toxicity: first evidence of a digestive Lactobacilli possessing a myrosinase-like activity in vivo.J. Sci. Food Agric. 52, 547, 1990.
• 4. VERHOEVEN D. T. H., VERHAGEN H., GOLDBOHM R. A., VAN BRANDT P. A., VAN POPPEL G. A review of mechanisms underlying anticarcinogenicity by brassica vegetables. Chemi Biol. Interact. 103, 79, 1997.
• 5. TALALAY P., FAHEY J. W. Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism. J. Nutr. 31(11 Suppl), 3027S, 2001.
• 6. TIEDINK H. G. M., MALINGRE C. E., VAN BROEKHOVEN L. W., JONGEN W. M. F., LEWIS J., FENWICK G. R. Role of glucosinolates in the formation of N-nitroso compounds. J. Agric. Food Chem. 39, 922, 1991.
• 7. MORENO D. A., CARVAJAL M., LÓPEZ-BERENGUER C., GARCIA-VIGUERA C. Chemical and biological characterisation of nutraceutical compounds of broccoli. J. Pharmaceut. And Biochem. Anal. 41, 1508, 2006.
• 8. MUKHERJEE S., GANGOPADHYAY H., DAS D. K. Broccoli: A Unique Vegetable That Protects Mammalian Hearts trough the Redox Cycling of the Thioredoxin Superfamily. J. Agric. Food Chem. 56, 609, 2008.
• 9. SMOLIŃSKA U., MORRA M. J., KNUDSEN G. R., JAMES R. L. Isotiocyanates Produced by Brassicaceae Species as Inhibitors of Fusarium oxysporum. Plant Disease 87 (4), 407, 2003.
• 10. MAJCHRZAK B., CISKA E., WALERYŚ Z. Glucosinolates extracted with seeds of the spring Cruciferae and their infuenze on the growth pathogenic fungi. Progres in Plant Protection 44 (2), 933, 2004 [In Polish].
• 11. CISKA E., MARTYNIAK-PRZYBYSZEWSKA B., KOZLOWSKA H. Content of Glucosinolates in Cruciferous Vegetables Grown at the Same Site for Two Years under Different Climatic Conditions. J. Agric. Food Chem. 48, 2862, 2000.
• 12. COLE R. A. Isothiocyanates, nitryles and thiocyjanates as products of autolysis of glucosinolates in Cruciferae. Phytochemistry, 15, 759, 1976.
• 13. BELLOSTAS N., KACHLICKI P., SØRENSEN J. C., SØRENSEN H. Glucosinolate profiling of seed and sprouts of B. oleracea varieties used for food. Scientia Horticulturae. 114, 234, 2007.
• 14. KREGER-VAN RIJ N. J. W. (red.): The Yeast, a taxonomical study. Els. Sci. Pabl. B. V. Amsterdam, 1984.
• 15. KURTZMAN C. P., FELL J. W.: The Yeast, A Taxonomic Study. Els. Sci. B. V. Amsterdam, 2000.
• 16. Official Journal of the European Communieties 1990. L 170. 33. 3 VII 1990.
• 17. PARK Y., CHOI B. H., KWAK J. S., KANG C. W., LIM H. T., CHEONG H. S., HAHM K. S. J. Kunitztype serine protease inhibitor from potato (Solanum tuberosum L. Cv. Jopung). Agric. Food Chem. 53 (16), 6491, 2005.
• 18. GAYOSO C. W., LIMA E. O., OLIVIERA V. T., PEREIRA P. O., SOUZA E. L., LIMA L. O., NAVARRO D. F. Sesitivity of fungi isolated from onychomycosis to Eugenia cariophyllata essential oil and eugenol. Fitoterapia, 76, 247, 2005.
• 19. GŁOWACKA A. Assignation of the epidemiological chain of dermatomycoses in selected Monastic and Ecclesiastic Theological Seminaries among the area of Lodź Archdiocese. Part III. Evaluation of antifungal properties of selected essential oils towards Candida albitans. Mikol. Lek. 10 (1), 15, 2003 [In Polish].
• 20. FREILE M. L., GIANNINI F., PUCCI G., STURNIOLO A., RODERO L., PUCCI O., BALZARETI V., ENRIZ R. D. Antimicrobial activity of aqueous extracts and of berberine isolated from Berberis heterophylla. Fitoterapia, 74, 702, 2003.
• 21. SHAMS-GHAHFAROKHI M., SHOKOOHAMIRI M.-R., AMIRRAJAB N., MOGHADASI B., GHAJARI A., ZEINI F., SADEGHI G., RAZZAGHI-ABYANEH M. In vitro antifungal activities of Allium cepa, Allium sativum and ketokonazole against some pathogenic yeast and dermatophytes. Fitoterapia, 77, 321, 2006.
• 22. KRAJEWSKA-KUŁAK E., ŁUKASZUK C., LEWKO J., NICZYPORUK W., WINTER G. Effects of grapefruit extract on the growth yeast-like fungi from Candida albicans strains. Mikol. Lek. 8 (2), 91, 2001 [In Polish].
• 23. SISTI M., AMAGLIANI G., BRANDI G. Antifungal activity of Brassica oleracea var. botrytis fresh aqueous juice. Fitoterapia; 74, 453, 2003.
• 24. DYNOWSKA M., BIEDUNKIEWICZ A., EJDYS E. Pathogenic Yeast-like Fungi with Bio-Indicator Properties. Pol. J. Env. Stud.; 10, suppl. I, 13, 2000.
• 25. DYNOWSKA M., EJDYS E., KISICKA I. Susceptibility to antifungal agents of yeasts-like fungi and yeasts isolated from people with multifocal infections. Mikol. Lek. 11 (1), 15, 2004.
• 26. TYCZKOWSKA-SIEROŃ E., KURNATOWSKI P. Analysis of correlation between flukonazole resistance and enzymatic activity of the Candida strains. Mikol. Lek. 13 (2), 99, 2006 [In Polish].