Chokeberry polyphenols reduce prooxidative influence of oxidized fats in rat diets

• Autorzy: Frejnagel S. S. , Zdunczyk Z.
• Języki publikacji: EN

Abstrakty

EN

The aim of the study was to estimate nutritional and physiological consequences of combined supplementation of rat casein diets with a strongly oxidized mixture of fats and extract of polyphenols from chokeberry. The experiment was conducted on 80 young Wistar rats divided into 8 groups. The animals were fed diets supplemented with 8% of fresh or oxidized fats and 0.4, 0.8 and 1.2% of polyphenol extract together. Addition of the oxidized fats caused significant reduction in animal growth without a decrease in nitrogen digestibility. On the other hand, the extract of polyphenols suppressed nitrogen utilization; animal growth was however similar to the control group. Analysis of the variance showed negative influence of the oxidized fats on cholesterol and triacyloglycerol concentration in the blood of the experimental animals. Increased activity of both aminotransferases in the blood of rats fed diets containing the oxidized fats indicated on liver malfunction. There was no effect of the experimental factors on the antioxidant status of the blood, but a dose-dependent reduced content of malonylodialdehyde in the blood of rats fed diets supplemented with the extract of polyphenols suggested that the extract had a preventive effect against prooxidative activity of the oxidized fats.

Słowa kluczowe

EN

fat; oxidized fat; polyphenol; chokeberry; rat; diet; animal nutrition; laboratory animal; prooxidative activity

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2008
• Tom: 11
• Numer: 2
• Opis fizyczny: p.125-132,fig.,ref.

Twórcy

autor

Frejnagel S. S.

• Polish Academy of Sciences, Tuwima 10, 10-747 Olsztyn, Poland

autor

Zdunczyk Z.

Bibliografia

• Ahmed AE, Smithard R, Ellis M (1991) Activities of enzymes of the pancreas and the lumen and mucosa of the small intestine in growing broiler cockerels fed on tannin-con­taining diets. Br J Nutr 65: 189-197.
• Alzueta C, Trevino J, Ortiz L (1992) Effect of tannins from faba beans on protein utilisation in rats. J Sci Food Agric 59: 551-553.
• AOAC (1990) Official Methods of Analysis of the Associ­ation of Official Analytical Chemists, 15th Ed., Boca Raton, Washington, DC.
• Bera D, Lahiri D, Nag A (2006) Studies on a natural anti­oxidant for stabilization of edible oil and comparison with synthetic antioxidants. J Food Engin 72: 542-545.
• Billek G, Guhr G, Sterner W (1979) Futterungsversuche mit erhitztem Fett und Fettfraktionen. Fette, Seifen, Anstrich- tmittel 81: 562-566.
• Bravo L, Manas E, Saura-Calixto F (1993) Dietary non-ex- tractable condensed tannins as indigestible compounds. Effect on feacal weight, protein and fat excretion. J Sci Food Agric 63: 63-68.
• Clark WL and Serbia GW (1991) Safety aspects of frying fat oils. Food Technol 45: 84-89.
• Cohn JS (2002) Oxidized fat in the diet, postprandial lipaemia and cardiovascular disease. Curr Opin Lipidology 13: 19-24.
• Engberg RM, Lauridsen C, Jensen SK, Jakobsen K (1996) Inclusion of oxidized vegetable oil in broiler diets. Its influ­ence on nutrient balance and on the antioxidative status of broilers. Poult Sci 75: 1003-1011.
• Frankel EN (1987) Secondary products of lipid oxidation. Chem Phys Lipids 44: 73-85.
• Frankel EN (1996) Antioxidants in lipid foods and their im­pact on food quality. Food Chem 57: 61-66.
• Frejnagel S (2007) Comparison of polyphenolic composition of extracts from honeysuckle, chokeberries and green tea - a short report. Pol J Food Nutr Sci 57: 83-86.
• Gardner FTW (1989) Oxygen radical chemistry of polyunsatu­rated fatty acids. Free Radic Biol Med 7: 65-86.
• Halliwell B (1994) Free radicals, antioxidant and human disease: curiosity, cause or consequence? Lancet 344: 721-724.
• Hayam I, Cogan U, Mokady S (1995) Dietary oxidized oil and the activity of antioxidant enzymes and lipoprotein peroxi­dation in rats. Nutr Res 13: 1037-1044.
• Hochgraf E, Mokady S, Cogan U (1997) Dietary oxidized linoleic acid modifies lipid composition of rat liver micro- somes and increases their fluidity. J Nutr 127: 681-686.
• Hochgraf E, Cogan U, Mokady S (2000) Dietary oxidized linoleic acid enhances liver cholesterol biosynthesis and secretion in rats. J Nutr Biochem 11: 176-180.
• Horigome T, Kumar R, Okamoto K (1988) Effects of con­densed tannins prepared from leaves of fodder plants on digestive enzymes in vitro and in the intestine of rats. Br J Nutr 60: 275-285.
• Juskiewicz J, Dlugoszewska M, Zdunczyk Z, Krasnod^bska- -Depta A, Krefft B, Sadowska J (2000) The response of rats to long-term feeding with diets containing oxidized fat. 2. Biochemical indicators in the serum, liver and bone mineralization. J Anim Feed Sci 9: 147-155.
• Kimura F, Iida A, Endo Y, Fuijmoto K (2004) Bottle choice tests for oxidized oil in rats. Phys Behaviour 82: 877-881.
• Koga T, Moro K, Nakamori K, Yamakoshi J, Hosoyama Y, Kataoka S, Ariga T (1999) Increase of antioxidative po­tential of rat plasma by oral administration of proan- thocyanidin-rich extract from grape seeds. J Agric Food Chem 47: 1892-1897.
• Kuo K-L, Weng M-S, Chiang C-T, Tsai W-J, Lin-Shiau S-Y, Lin J-K (2005) Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh and green tea leaves in rats. J Agric Food Chem 53: 480-489.
• Lermer CM, Mattes RD (1999) Perception of dietary fat: ingestive and metabolic implications. Prog Lipid Res 38: 117-128.
• Levrat MA, Texier O, Regerat F, Demigne C, Remesey C (1993) Comparison of the effects of condensed tannin and pectin on cecal fermentations and lipid metabolism in the rat. Nutr Res 13: 427-433.
• Lin CF, Ashghar A, Gray JI, Buckley DJ, Booren AM, Crackel RL, Flegal CJ (1989) Effects of oxidized dietary oil and antioxidant supplementation on broiler growth and meat stability. Br Poultry Sci 39: 855-864.
• Liu JF, Huang CJ (1996) Dietary oxidized frying oil enhances tissue alpha-tocopherol depletion and radioisotope tracer excretion in vitamin E-deficient rats. J Nutr 126: 2227-2235.
• Lopez-Varela S, Sanchez-Muniz FJ, Cuesta C (1995) De­creased food efficiency ratio, growth retardation and changes in liver fatty acid composition in rats consuming thermally oxidized and polymerized sunflower oil used for frying. Food Chem Toxic 33: 181-189.
• Martin-Carron N, Saura-Calixto F, Goni I (2000) Effects of dietary fibre- and polyphenol rich grape products on lipidaemia and nutritional parameters in rats. J Sci Food Agric 80: 1183-1188.
• Mehansho H, Hagerman A, Clements S, Butler LG, Rodler JC, Carlson DM (1983) Modulation of proline-rich pro­tein biosynthesis in rat parotid glands by sorghums with high tannin levels. Proc Natl Acad Sci 80: 3948-3952.
• Mitjavilla S., Lacombe C., Carrera G., Derache R. (1977) Tannic acid and oxidized acid on the functional state of rat intestinal epithelium. J Nutr 107: 2113-2121.
• Moreiras-Varela O, Ruiz-Roso B, Varela G (1988) Effects of frying on the nutritive value of food. In: Varela G, Bender
• AE, Morton DI (eds) Frying of food. Principles, Changes, New approaches. Section 6, Ellis Horwood, Chichester, pp 93-102.
• Nielsen HK, Finot PA, Hurrell RF (1985) Reactions of pro­teins with oxidizing lipids. 2. Influence on protein quality and on the availability of lysine, methionine, cysteine and trypthophan as measured in rat assays. Br J Nutr 53: 75-86.
• Owu DU, Osim EE, Ebong PE (1998) Serum liver enzymes profile of Wistar rats following chronic consumption of fresh or oxidized palm oil diets. Acta Tropica 69: 65-73.
• Polish Central Statistical Office (2001) Statistical yearbook of the Republic of Poland, Statistical Publishing Estab­lishment, Warsaw.
• Reeves P (1997) AIN-93 purified diets for laboratory ro­dents: final report of the American Institute of Nutrition ad hoc writing committee on the reformation of the AIN-76A rodent diet. J Nutr 123: 1939-1951.
• Sanchez-Muniz FJ, Higon E, Cava F, Viejo JM (1992) Pre­vention of dietary hypercholesterolemnia in rats using sunflower oil fried sardines. Effects on cholesterol and serum enzymes. J Sci Food Agric 40: 2226-2231.
• Sarni-Manchado P, Cheynier V, Moutounet M (1999) Inter­actions of grape seed tannins with salivary proteins. J Ag­ric Food Chem 47: 42-47.
• Sheehy PJA, Morissey PA, Flynn A (1994) Consumption of thermally oxidized sunflower oil by chicks reduces h-tocopherol status and increases susceptibility of tissues to lipid oxidation. Br J Nutr 71: 53-65.
• Stanley LL and Mazier MJP (1999) Potential explanations for the French paradox. Nutr Res 19: 3-15.
• Turek JJ, Watkins BA, Schoenlein IA, Allen KGD, Hayek MG, Aldrich CG (2003) Oxidized lipid depress canine growth, immune function and bone formation. J Nutr Biochem 14: 24-31.
• Vallet J, Rouanet J-M, Besancon P (1994) Dietary grape seed tannins: effects on nutritional balance and on some enzymatic activities along the crypt-villus axis of rat small intestine. Ann Nutr Metab 38: 5-84.
• Varela G, Moreira-Varela O, Ruiz-Roso B, Conde R (1986) Influence of repeated frying on digestive utilization of various fats. J Sci Food Agric 37: 487-490.
• Wang S-Y, Bottje W, Maynard P, Dibner J, Shermer W (1997) Effect of Santoquin® and oxidized fat on liver and intestinal glutathione in broilers. Poultry Sci 76: 961-967.
• Yuste P, Longstaf M, McCorquodale C (1992) The effect of proanthocyanidin-rich hulls and proanthocyanidin ex­tracts from bean (Vicia faba L.) hulls on nutrient digesti­bility and digestive enzyme activity in young chicks. Br J Nutr 67: 57-65.
• Zdunczyk Z, Juskiewicz J, Dlugoszewska M, Frejnagel S, Koncicki A (2000) The response of rats to long- -term feeding with diets containing oxidized fat. 1. Thermooxidative changes in fat, body weight gain, feed consumption and utilization. J Anim Feed Sci 9: 137-146.
• Zdunczyk Z, Frejnagel S, Wroblewska M, Juskiewicz J, Os- zmianski J, Estrella I (2002) Biological activity of poly­phenols extracted from different plant sources. Food Res Int 35: 183-186.