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2005 | 46 | 4 |

Tytuł artykułu

A novel polymorphism in exon 1 of the porcine myogenin gene

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Myogenin is a gene belonging to the MyoD family, which codes for the bHLH transcription factor playing a key role in myogenesis. It affects the processes of differentiation and maturation of myotubes during embryogenesis. Fragments of the porcine myogenin coding sequence and promoter region were amplified and subjected to MSSCP analysis. T—>C transition recognised by the Mae III restriction enzyme in exon 1 was revealed, which appeared to be a silent mutation in the region of the transactivation domain. No other polymorphism was found either in the remaining coding sequence or the promoter region.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

46

Numer

4

Opis fizyczny

p.399-402,fig.,ref.

Twórcy

  • Polish Academy of Sciences, Jastrzebiec, Postepu 1, 05-552 Wolka Kosowska, Poland
autor

Bibliografia

  • Buckingham M, 1992. Making muscle in mammals. Trends Genet 8: 144-148.
  • Cieślak D, Kapelański W, Blicharski T, Pierzchała M, 2000. Restriction fragment length polymorphism in myogenin and myß genes and their influence on lean meat content in pigs. J Anim Breed Genet 117: 43-55.
  • Cieślak D, Kurył J, Kapelański W, Pierzchała M, Grajewska S, Bocian M, 2002. A relationship between genotypes at MYOG, MYF3 and MYF5 loci and carcass meat and fat deposition traits in pigs. Anim Sci Pap Rep 20: 77-92.
  • Hasty P, Bradley A, Morris JH, Edmondson DG, Venuti JM, Olson EN, Klein WH, 1993. Muscle deficiency and neonathal death in mice with targeted mutation in the myogenin locus. Nature 364: 501-506.
  • Kawasaki ES, 1990. Sample preparation from blood, cells and other fluids. In: Innis GH, Gelfand DH, Sninsky JJ, White TJ, eds. PCR Protocols: A guide to methods and applications. Acad. Press: New York: 3-12.
  • Lassar AB, Buskin JN, Lockshon D, Davis RL, Apone S, Hauschka SD, Weintraub H, 1989. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell 58: 823-831.
  • Mendez EA, Emst CW, Rothschild MF, 1997. Rapid communication: a novel DNA polymorphism of the porcine myogenin (MYOG) gene. J Anim Sci 75: 1984.
  • Montarras D, Chelly J, Bober E, Arnold H, Ott M-O, Gros F, Pinset C, 1991. Developmental patterns in the expression of Myf-5, MyoD, myogenin and MRF4 during myogenesis. New Biol 3: 592-600.
  • Nabeshima Y, Hanaoka K, Hayasaka M, Esumi E, Li S, Nonaka I, Nabeshima Y-I, 1993. Myogenin gene disruption results in perinatal lethality because of severe muscle defects. Nature 364: 532-535.
  • Nowak Z, Hermanowicz-Świerczek A, Charon KM, Kulisiewicz J, 2003. Conformation polymorphism in myogenin gene in pigs. Anim Sci Pap Rep 21: 277-282.
  • Schwarz JJ, Chakraborty T, Martin J, Zhou J, Olson EN, 1992. The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription. Mol Cell Biol 12: 266-275.
  • Soumillion A, Erkens JHF, Lenstra JA, Rettenberger G, te Pas MFW, 1997. Genetic variation in porcine myogenin gene locus. Mamm Genome 8: 564-568.
  • Weintraub H, Tapscott SJ, Davis RL, Thayer MJ, Adam MA, Lassar AB, Miller D, 1989. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci USA 86: 5434-5438.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-683e4977-4144-47e9-92ce-0906586a3d94
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