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2009 | 65 | 07 |

Tytuł artykułu

Erlichioza psow w swietle przypadku wlasnego

Warianty tytułu

EN
Erlichiosis in dogs - an own case

Języki publikacji

PL

Abstrakty

EN
In April 2008 a two-year-old dog of the Leonberger race with symptoms of apathy, loss of appetite and with the temperature 40.1°C was brought to the Veterinary Polyclinic of the University of Warmia and Mazury in Olsztyn The hematological examinations showed a slight thrombocytopenia, and a routinely performed blood smear for the presence of Babesia canis gave a negative result. Despite administering antipyretic and antibiotic, the condition of the patient deteriorated in the following twenty-four hours. The repeated blood tests showed deepening thrombocytopenia, worsening red blood cell indicators and an increase in the activity of alanine aminotransferase and aspartate aminotransferase, as well as the level of urea and creatinin. The repeated blood smear for B. canis gave a positive result at that time. Treatment for babesiosis was applied including the administration of imidocarb, intravenous infusions and diuresis-supporting medicines. In the following days the condition of the dog relapsed in spite of the treatment. Additional symptoms appeared, such as difficult breathing, serous nostril and conjunctival outflow, loss of body weight, pallor of mucous membranes, vomiting, reluctance to move and a deteriorating dyspnea. Blood examinations showed growing leukocytosis and granulocytosis as well as RBC, HGB, HCT and PLT levels remaining considerably below physiological norms. In the blood smear, performed again, the presence of blue-staining inclusion bodies, which were identified as the morula of Ehrlichia canis, was observed in single monocytes. The diagnosis was confirmed with the immunochromatographic test. As a treatment, oxytetracycline was applied intravenously for 7 days, followed by doxycycline administered orally for 5 weeks. The patient’s condition required also the application of full tinned blood, as well as the usage of intravenous infusions and diuretic for several days. During five days from the beginning of the therapy with tetracyclines the clinical condition of the dog and the blood examination results were strongly improved and returned to the physiological norm during two weeks following the end of the antibiotic therapy.

Wydawca

-

Rocznik

Tom

65

Numer

07

Opis fizyczny

s.480-483,tab.,bibliogr.

Twórcy

  • Uniwersytet Warminsko-Mazurski w Olsztynie, ul.Oczapowskiego 13, 10-719 Olsztyn
autor

Bibliografia

  • 1. Adaszek Ł.: Wybrane aspekty epidemiologii babeszjozy, boreliozy i erlichiozy psów. Praca dokt., Akademia Rolnicza, Lublin 2006.
  • 2. Buonavoglia D., Sagazio P., Gravino E. A., De Capraris D., Cerundolo R., Buonavoglia C.: Serological evidence of Ehrlichia canis in dogs in southern Italy. New Microbiol. 1995, 18, 83-86.
  • 3. Dumler J. S., Bakken J. S., Richter P., Kimsey R., Madigan J. E.: Serologic cross-reactions among Ehrlichia equi, Ehrlichia phagocytophila and human granulocytic Ehrlichia. J. Clin. Microbiol. 1995, 33, 1098-1103.
  • 4. Dumler J. S., Barbet A. F., Bekker C. P., Dasch G. A., Palmer G. H., Ray S. C., Rikihisa Y., Rurangrirwa F. R.: Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and "HGE agent" as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 2001, 51, 2145-2165.
  • 5. Goethe R.: Ehrlichia canis - Infektionen der Hunde in Deutschland. Tierärztl. Prax. 1998, 26, 396-401.
  • 6. Harrus S., Aroch J., Lavy E., Bark H.: Clinical manifestations of infectious canine cyclic thrombocytopenia. Vet. Rec. 1997, 141, 247-250.
  • 7. Harrus S., Kass P. H., Klement E., Waner T.: Canine monocytic ehrlichiosis: a retrospective study of 100 cases and an epidemiological investigation of prognostic indicators for the disease. Vet. Rec. 1997, 139, 360-363.
  • 8. Igbal Z., Rikihisa Y.: Reisolation of Ehrlichia canis from blood and tissues of dogs after doxycycline treatment. Vet. Microbiol. 1994, 32, 1644-1649.
  • 9. Inokuma H., Oyamada M., Kelly P. J., Jacobson L. A., Fournier P.-E., Itamoto K., Okuda M., Brouqui P.: Molecular detection of a new Anaplasma species closely related to Anaplasma phagocytophilum in canine blood from South Africa. J. Clin. Microbiol. 2005, 43, 2934-2937.
  • 10. Keefe T. J., Holland C. J., Salyer P. E., Ristic M.: Distribution of Ehrlichia canis among military working dogs in the world and selected civilian dogs in the United States. J. Am. Vet. Med. Assoc. 1982, 181, 236-238.
  • 11. Kuehn F., Gaunt S.: Clinical and hematologic findings in canine ehrlichiosis. J. Am. Med. Vet. Assoc. 1985, 186, 355-358.
  • 12. Matthewman L. A., Kelly P. J., Bobde P. A., Tagwira M., Mason P. R., Majok A., Brouqui P., Raoult D.: Infections with Babesia canis and Ehrlichia canis in dogs in Zimbabwe. Vet. Rec. 1993, 133, 344-346.
  • 13. McBride J. W., Corstvet R. E., Gaunt S. D., Chinsangaram J., Akita G. Y., Osburn B. I.: PCR detection of acute Ehrlichia canis infection in dogs. Vet. Diagn. Invest. 1996, 8, 441-447.
  • 14. Płoneczka K.: Badania epizootiologiczne nad występowaniem erlichiozy psów na terenie Polski. Praca dokt., Wydz. Medycyny Weterynaryjnej UP, Wrocław 2004.
  • 15. Płoneczka K., Śmielewska-Łoś E.: Występowanie przeciwciał swoistych dla Ehrlichia canis u psów z terenu południowo-zachodniej Polski. Medycyna Wet. 2003, 59, 1005-1008.
  • 16. Pusterla N., Chang C. C., Chomel B. B., Chae J. S., Foley J. E., DeRock E., Kramer H., Lutz V. L., Madigan J. E.: Serologic and molecular evidence of Ehrlichia sp. in coyotes in California. J. Wildl. Dis. 2000, 36, 494-499.
  • 17. Pyle R. L.: Canine ehrlichiosis. J. Am. Vet. Med. Assoc. 1980, 177, 1197-1199.
  • 18. Randolph S.: Predicting the risk of tick-borne diseases. Int. J. Microbiol. 2002, 33, suppl., 6-10.
  • 19. Rikihisa Y.: The tribe Ehrlichiae and ehrlichial diseases. Clin. Microbiol. Rev. 1991, 4, 286-308.
  • 20. Sainz A., Tesouro M. A., Amusategui I., Rodriguez F., Mazzucchelli F., Rodriguez M.: Prospective comparative study of 3 treatment protocols using doxycycline or imidocarb diproprionate in dogs with naturally occurring ehrlichiosis. J. Vet. Intern. Med. 2000, 14, 134-139.

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Bibliografia

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