Novel properties of antimicrobial peptides

• Autorzy: Kamysz W. , Okroj M. , Lukasiak J.
• Języki publikacji: EN

Abstrakty

EN

Endogenous peptide antibiotics are known as evolutionarily old components of in­nate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.

Słowa kluczowe

EN

cell membrane; cell; peptide; immunity; immune system; membrane; antibiotic; mitogen; signalling pathway; antimicrobial peptide; tumour; immune response

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2003
• Tom: 50
• Numer: 2
• Opis fizyczny: p.461-469,fig.

Twórcy

autor

Kamysz W.

• Medical University of Gdansk, Gdansk, Poland

autor

Okroj M.

autor

Lukasiak J.

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