Antibacterial activity of thermally modified lysozyme

• Autorzy: Lesnierowski G. , Cegielska-Radziejewska R. , Kijowski J.
• Języki publikacji: EN

Abstrakty

EN

Lysozyme (EC 3.2.1.17, mucopeptyde N-acetylmuramic-hydrolase) exhibits the ability to destroy cell walls of Gram-positive bacteria. The range of activity for this enzyme may be extended through modifications, as a result of which polymerized forms of lysozyme are obtained. It was found that lysozyme dimer exhibits bacteriostatic properties towards both Gram-positive and Gram-negative bacteria. The aim of the study was to determine the conditions of thermal modification of lysozyme and to assess the antibacterial action of this enzyme after modification. The dimer content in the modified lysozyme preparations depended on the pH and concentration of a given solution. It was found that modified lysozyme was characterized by higher antibacterial activity towards Micrococcus luteus and Escherichia coli in comparison to the unmodified form of the enzyme.

Słowa kluczowe

EN

lysozyme monomer; Micrococcus luteus; antibacterial activity; pH value; lysozyme dimer; Escherichia coli; hydrolytic activity

• Wydawca: -
• Czasopismo: Electronic Journal of Polish Agricultural Universities. Series Food Science and Technology
• Rocznik: 2001
• Tom: 04
• Numer: 2
• Opis fizyczny: http://www.ejpau.media.pl

Twórcy

autor

Lesnierowski G.

• August Cieszkowski Agricultural University of Poznan, Wojska Polskiego 31, 60-624 Poznan, Poland

autor

Cegielska-Radziejewska R.

autor

Kijowski J.

Bibliografia

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