Association of PIT1, GH and GHRH polymorphisms with performance and carcass traits in Landrace pigs

• Autorzy: Franco M M , Antunes R C , Silva H D , Goulart L R
• Języki publikacji: EN

Abstrakty

EN

The study of candidate genes, based on physiological effects, is an important tool to identify genes to be used in marker-assisted selection programs. In this study, a group of halothane gene-free, non-castrated, male Landrace pigs was used to study the association between polymorphisms in the PIT1 (n = 218), GH (n = 213) and GHRH (n = 206) genes and fat thickness, average daily gain, and the EPD (expected progeny difference) for fat thickness, average daily gain, and litter size. These genes are potential candidate markers because of their important physiological effects. The pigs were genotyped by PCR-RFLP, and the statistical model used to analyze the association between genotypes and the traits measured included genotypes as a fixed effect and age and weight as covariates. PIT1 polymorphisms were associated with fat thickness (P = 0.0019), EPD for average daily gain (P = 0.0001) and EPD for fat thickness (P = 0.0001), whereas GH polymorphisms were associated with fat thickness (P = 0.0326) and average daily gain (P = 0.0127), and GHRH polymorphisms were associated with the average daily gain (P = 0.0001) and EPD for fat thickness (P = 0.0004). These results confirmed the potential usefulness of these genes in marker-assisted selection programs for pig breeding.

Słowa kluczowe

EN

pig; growth hormone releasing hormone; carcass trait; polymorphism; growth hormone releasing hormone receptor; molecular genetics; Landrace pig; growth hormone; performance; growth hormone receptor

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2005
• Tom: 46
• Numer: 2
• Opis fizyczny: p.195-200,ref.

Twórcy

autor

Franco M M

• Laboratory of Molecular Genetics, Institute of Genetics and Biochemistry, Federal University of Uberlandia, Uberlandia, MG, Brazil
• Laboratory of Animal Molecular Genetics, EMBRAPA Genetics Resources and Biotechnology, Brasilia, DF, Brazil

autor

Antunes R C

• Laboratory of Molecular Genetics, Institute of Genetics and Biochemistry, Federal University of Uberlandia, Uberlandia, MG, Brazil

autor

Silva H D

• Institute of Mathematics, Federal University of Uberlandia (UFU), Uberlandia, MG, Brazil

autor

Goulart L R

• Laboratory of Molecular Genetics, Institute of Genetics and Biochemistry, Federal University of Uberlandia, Uberlandia, MG, Brazil

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