Selenium protection against cadmium toxicity in hamster embryos

• Autorzy: Wlodarczyk B , Minta M. , Biernacki B. , Szkoda J. , Zmudzki J.
• Języki publikacji: EN

Abstrakty

EN

The present studies were carried out in order to assess the protective effects of selenium against cad­mium toxicity in pregnant hamsters. On the 8th day of gestation the females were dosed subcutaneously either with cadmium or with cadmium and selenium in the following doses (mg per kilogram of body weight): 0, 1 Cd, 1 Cd + 1 Se, 2 Cd, 2 Cd + 2 Se. In groups treated with cadmium decreased litter size, increased postimplantation losses, reduced foetal weight, elevated percentage of resorptions and increased incidence of malformations were noted. Injection of Cd and Se resulted in significantly lower embryo- and foetotoxic indices. Selenium also reduced Cd concentrations in maternal tissues but not in the placenta nor in the foetuses.

Słowa kluczowe

EN

cadmium toxicity; cadmium distribution; toxicity; protection; animal; cadmium; hamster; selenium; embryo

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2000
• Tom: 09
• Numer: 4
• Opis fizyczny: p.323-327,fig.

Twórcy

autor

Wlodarczyk B

• National Veterinary Research Institute, 57 Partyzantow Av., 24-100 Pulawy, Poland

autor

Minta M.

autor

Biernacki B.

autor

Szkoda J.

autor

Zmudzki J.

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