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2007 | 63 | 10 |

Tytuł artykułu

Surowicze stezenie cystatyny C i aktywnosc antytrypsynowa w chorobach zakaznych kur

Warianty tytułu

EN
Serum concentration of cystatin and antitrypsin activity in chicken infection diseases

Języki publikacji

PL

Abstrakty

EN
The aim of the study was to determine the influence of some pathogens on the serum level and dynamics of chicken cystatin and a1-protease inhibitor. The experiment was carried out on 150 Starbro chickens that were randomly selected into 6 groups. Group I was the control, group II and III were infected with REO virus and Marek's disease virus, group IV with invasive Eimeria oocysts, and V and VI with E. coli and S. aureus respectively. The level of chicken cystatin was determined by ELISA test and a1-protease inhibitor as an antitrypsin capacity. It was demonstrated that the concentration of chicken cystatin increased in chickens with the virus infection REO and MDV by about 54% and 29%, while with E. coli and S. aureus by 43%. The smallest changes, observed in chickens infected with Eimeria oocyst, amounted to 16%. In contrast, the authors only observed an increase of the level a1-protease inhibitor in coccidiosis. The authors postulate that chicken cystatin is more useful as a diagnostic parameter than a1-protease inhibitor in the analysed diseases.

Wydawca

-

Rocznik

Tom

63

Numer

10

Opis fizyczny

s.1216-1219,tab.,bibliogr.

Twórcy

autor
  • Akademia Medyczna we Wroclawiu, ul.Szewska 38/39, 50-139 Wroclaw
autor
autor

Bibliografia

  • 1.Amrani D. L., Mauzy-Melitz D., Mosesson M. W.: Effect of hepatocyte- -stimulating factor and glucocorticoids on plasma fibronectin levels. Biochem. J. 1986, 238, 365-371.
  • 2.Anastasi A., Brown M. A., Kembhavi A. A., Nicklin M. J., Sayers C. A., Sunter D. C., Barrett A. J.: Cystatin, a protein inhibitor of cysteine proteinases. Biochem. J. 1983, 211, 129-138.
  • 3.Bradford M. M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
  • 4.Chamanza R., Toussaint M. J., van Ederen A. M., van Veen L., Hulskamp-Koch C., Fabri T. H.: Serum amyloid A and transferrin in chicken. A preliminary investigation of using acute-phase variables to assess diseases in chickens. Vet. Q. 1999, 21, 158-162.
  • 5.Gaweł A., Mazurkiewicz M., Jurowski J.: Efektywność szczepionki Immucox w zapobieganiu kokcydiozie kur. Medycyna Wet. 2005, 61, 548-552.
  • 6.Gerbes A. L., Gulberg V., Bilzer M., Vogeser M.: Evaluation of serum cystatin C concentration as a marker of renal function in patients with cirrhosis of the liver. Gut 2002, 50, 106-110.
  • 7.Gołąb K., Gburek J., Gaweł A., Warwas M.: Changes in chicken egg white cystatin concentration and isoforms during embryogenesis. Brit. Poultry Sci. 2001, 42, 394-398.
  • 8.Gołąb K., Warwas M.: Białka jaja kurzego właściwości biochemiczne i zastosowania. Adv. Clin. Exp. Med. 2005, 14, 1001-1010.
  • 9.Grieninger G., Liang T. J., Beuving G., Goldfarb V., Metclfe S., Muller-Eberhard U.: Hemopexin is developmentally regulated, acute-phase plasma protein in chicken. J. Biol. Chem. 1986, 261, 15719-15724.
  • 10.Holt P. S., Gast R. K.: Comparison of the effects of infection with Salmonella enteritidis, in combination with an induced molt, on serum levels of the acute phase protein, alpha1 acid glycoprotein, in hens. Poult. Sci. 2002, 81, 1295-300.
  • 11.Karnaukhova E., Ophir Y., Golding B.: Recombinant human alpha-1 proteinase inhibitor: towards therapeutic use. Amino Acids 2006, 30, 317-332.
  • 12.Kostro K., Wojcicka-Lorenowicz K., Gliñski Z., Krakowski L., Wrona Z.: Białka ostrej fazy jako ligandy komórek układu immunologicznego. Medycyna Wet. 2002, 58, 929-933.
  • 13.Lisowska-Myjak B., Pachecka J.: Antigenic and functional levels of alpha-1-antitrypsin in serum during normal and diabetic pregnancy. Eur. J. Obstet. Gynecol. Reprod. Biol. 2003, 106, 31-35.
  • 14.Mazur-Gonkowska B., Koncicki A.: Białka ostrej fazy u ptaków występowanie i charakterystyka. Medycyna Wet. 2002, 58, 925-928.
  • 15.Mazurkiewicz M.: Choroby drobiu. WAR, Wrocław 2005, 186-425.
  • 16.Mussap M., Plebani M.: Biochemistry and clinical role of human cystatin C. Crit. Rev. Clin. Lab. Sci. 2004, 41, 467-550.
  • 17.Pafrey H., Mahadeva R., Lomas D. A.: a1-antitrypsin deficiency, liver disease and emphysema. Int. J. Bioch. Cell Biol. 2003, 35, 1009-1014.
  • 18.Schön H., Räster B.: Untersuchungen über die Trypsininhibitor Kapazität des menschlichen Serums. Clin. Chim. Acta 1962, 7, 571-587.
  • 19.Takahashi M., Tezuka T., Korant B., Katunuma N.: Inhibition of cysteine protease and growth of Staphylococcus aureus V8 and poliovirus by phosphorylated cystatin alpha conjugate of skin. Biofactors 1999, 10, 339-345.
  • 20.Takeuchi S., Kinoshita T., Kaidoh T., Hashizume N.: Purification and characterization of protease produced by Staphylococcus aureus isolated from a diseased chicken. Vet. Microbiol. 1999, 67, 195-202.
  • 21.Tohjo H., Miyoshi F., Uchida E., Niiyama M., Syuto B., Moritsu Y., Ichikawa S., Takeuchi M.: Polyacrylamide gel electrophoretic patterns of chicken serum in acute inflammation induced by intramuscular injection of turpentine. Poult. Sci. 1995, 74, 648-655.
  • 22.Trziszka T., Saleh Y, Kopeć W., Siewiñski M., Wesierska E.: Effect of hen's age on the level of cystatin in the chicken egg white. Int. J. Poult. Sci. 2004, 3, 471-477.
  • 23.Verdot L., Lalmanach G., Vercruysse V., Hoebeke J., Gauthier F., Vray B.: Chicken cystatin stimulates nitric oxide release from interferon-gamma-activated mouse peritoneal macrophages via cytokine synthesis. Eur. J. Biochem. 1999, 266, 1111-1117.
  • 24.Wesierska E., Saleh Y., Trziszka T., Kopeæ W., Siewiñski M., Korzekwa K.: Antimicrobial activity of chicken egg white cystatin. World J. Microbiol. Biotechnol. 2005, 21, 59-64.
  • 25.Xie H., Newberry L., Clark F. D., Huff W. E., Huff G. R., Balog J. M., Rath N. C.: Changes in serum ovotransferrin levels in chickens with experimentally induced inflammation and diseases. Avian Dis. 2002, 46, 122-131.
  • 26.Yun C. H., Lillehoj H. S., Lillehoj E. P.: Intestinal immune responses to coccidiosis. Develop. Comp. Immunol. 2000, 24, 303-324.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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