EN
Immunogenic properties of a two-component autovaccine against enterotoxemia and braxy of sheep based on C. perfringens D and C. septicum toxoids have been evaluated. Experiments on 49 pregnant sheep immunized 3-2 weeks before parturition and on 50 lambs at the age of 2-3 months vaccinated twice, showed that the prepared autovaccine induced antibodies against e-toxin and a-toxin at a titre of 4-64 antitoxic units/ml in sheep and 8-64 antitoxic units/ml in lambs. An induced level of antitoxic antibodies protected lambs in a fattening period against enterotoxemia and braxy and sheep against C. septicum toxoinfection.