Antiparasitic properties of homoallylamines and related compounds

• Autorzy: Gomez-Barrio A , Montero-Pereira D. , Nogal-Ruiz J.J. , Escario J.A. , Muelas-Serrano S. , Kouznetsov V.V. , Vargas Mendez L.Y. , Urbina Gonzales J.M. , Ochoa C.
• Języki publikacji: EN

Abstrakty

EN

A study of some antiparasitic properties of several homoallylamines and related tetrahydroquinolines and quinolines, previously described, was carried out using in vitro activity assays against the epimastigote form of Trypanosoma cruzi and against Trichomonas vaginalis. Unspecific cytotoxicity against murine macrophages was also studied. Although the antichagasic and trichomonacidal activities are not comparable to those of the standard drugs, nifurtimox and metronidazole, some of the compounds exhibit an interesting specific antiparasitic activity.

Słowa kluczowe

EN

murine macrophage; tetrahydroquinoline; chemical structure; antiparasitic property; homoallylamine; quinoline; unspecific cytotoxicity

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 2006
• Tom: 51
• Numer: 1
• Opis fizyczny: p.73-78,fig.,ref.

Twórcy

autor

Gomez-Barrio A

• Universidad Complutense, 28040 Madrid, Spain

autor

Montero-Pereira D.

autor

Nogal-Ruiz J.J.

autor

Escario J.A.

autor

Muelas-Serrano S.

autor

Kouznetsov V.V.

autor

Vargas Mendez L.Y.

autor

Urbina Gonzales J.M.

autor

Ochoa C.

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