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2004 | 63 | 1 |

Tytuł artykułu

Green tea as an antioxidant which protects against alcohol induced injury in rats - a histopathological examination

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Our study with animal models was designed to test the hypothesis that green tea protects against chronic (over 4 weeks) alcohol induced liver injury in rats. The research was conducted on Wistar male rats divided into 4 research groups: I — received the Libera-De Carli control diet (L-DC), II — received (L-DC) and green tea, III — received (L-DC) and ethanol and IV — received (L-DC), green tea and ethanol. When comparing groups I and II we saw less intensive steatosis in group II than in group I, which can suggest that green tea may affect the accumulation of fat in the hepatocytes and protect them against steatosis and disruption. In III, the ethanol group, the steatosis of the liver increased considerably and the green tea which was given with ethanol in group IV did not halt this, as in group IV we also observed intensive steatosis in the liver. From this data we conclude that green tea has an important, although not fully understood role in preventing liver injury.

Słowa kluczowe

Wydawca

-

Czasopismo

Rocznik

Tom

63

Numer

1

Opis fizyczny

p.123-126,fig.,ref.

Twórcy

autor
  • Medical University of Bialystok, Waszyngtona 13, 15-269 Bialystok, Poland
autor
autor
autor

Bibliografia

  • 1. Aleynik SI, Leo MA, Aleynik MK, Lieber CS (1998) Increase circulating products of lipid peroxidation in patients with alcoholic liver disease. Alcohol Clin Exp Res, 22: 192–196.
  • 2. Yang M, Wang C, Chen H (2001) Green, oolong andblac tea extracts mo-dulate lipid metabnolism in hyperlipidemia rats fed high-sucrose diet. J Nutr Biochem, 12: 14–20.
  • 3. Polavarapu R, Spitz DR, Sim JE (1998) Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver diets high in corn oil and fish oil. Hepatology, 27: 1317–1323.
  • 4. Princen HMG, van Duyvenvoorde W, Buytenhet R, Blonk C, Tijburg LLB, Langius JA, Mein-ders AE, Pijl H (1998) No effect of consumption of green and black tea on plasma lipid and anti-oxidant levels and on LDL oxidation in smokers. Arterioscler Thromb Vasc Biol, 18: 833–841.
  • 5. Skrzydlewska E, Ostrowska J, Stankiewicz A, Farbiszewski R (2002) Green tea as a potent antioxidant in alcohol intoxication. Addict Biol, 7: 307–314.
  • 6. Van het Hof KH, de Boer HSM, Wiseman SH, Lien N, Weststrate JA, Tijburg LBM (1997) Consumption of green or black tea does not increase resistance of lowdensity lipoprotein to oxidation in humans. Am J Clin Nutr, 66: 1125–1132.

Typ dokumentu

Bibliografia

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