Evaluation of bone formation in fetal skeletons following prenatal paracetamol administration in single alizarin-stained specimens in Wistar rats

• Autorzy: Burdan F
• Języki publikacji: EN

Abstrakty

EN

The study was undertaken to evaluate the effect of paracetamol on skeleton in Wistar rats. The drug was administered orally, once a day, in three doses: P1 — 3.5 mg/kg, P2 — 35.0 mg/kg, P3 — 350.0 mg/kg. The foetuses were delivered by laparotomy on the 21st day of pregnancy and fixed in alcohol. The skeletons were stained with alizarin. Insignificant differences of bone malformations were found.

Słowa kluczowe

EN

pregnancy; bone formation; acetaminophen; Wistar rat; reproductive toxicology; anatomy; fetal skeleton; fetus; rat; paracetamol

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2000
• Tom: 59
• Numer: 3
• Opis fizyczny: p.167-171,fig.

Twórcy

autor

Burdan F

• Medical University School of Lublin, Spokojna 1, 20-074 Lublin, Poland

Bibliografia

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