Collagen of umbilical cord vein and its alterations in pre-eclampsia

• Autorzy: Romanowicz L. , Jaworski S.
• Języki publikacji: EN

Abstrakty

EN

The state of the vascular system of the mother and of placenta is known to exert a great influence on intrauterinal development of the fetus. Pre-eclampsia is the most common pathological syndrome connected with pregnancy. Since collagen is one of the main constituents of the vessel wall a comparison was made with collagen content and its molecular polymorphism in umbilical cord veins of newborns from healthy and pre-eclamptic mothers. It was found that umbilical cord veins of newborns from moth­ers with pre-eclampsia contained 18% less collagen than those of the newborns from normal pregnancies. This decrease was accompanied by a slight decrease of collagen solubility, but all its types (I, III, IV, V and VI) were present. However, the umbilical vein wall of newborns from mothers with pre-eclampsia contained relatively less of type I and more of type III collagen than the normal umbilical cord. These differences may be connected with a disturbance of blood flow in fetus of a woman with pre-eclampsia.

Słowa kluczowe

EN

vascular system; alteration; pre-eclampsia; umbilical cord vein; mother; pathological syndrome; umbilical cord artery; collagen; placenta

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2002
• Tom: 49
• Numer: 2
• Opis fizyczny: p.451-458,fig.

Twórcy

autor

Romanowicz L.

• Medical Academy of Bialystok, A.Mickiewicza 2, 15-230 Bialystok, Poland

autor

Jaworski S.

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