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2006 | 62 | 12 |

Tytuł artykułu

Effect of praziquantel on Dicrocoelium dendriticum in naturally infected sheep

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Dicrocoeliosis is poorly known and often underestimated by studies and practitioners in many countries. The prophylaxis of Dicrocoelium has been difficult and unsatisfactory to date due to the complexity of its biological life cycle and epidemiology (Otranto and Traversa, 2002). This study was performed to evaluate the efficacy of praziquantel at 50 mg/kg b.w. against D. dendriticum. Thirty-four sheep (11 male + 13 female), naturally infected with D. dendriticum, were allocated to two groups as follows: Treatment group 50.0 mg/kg b.w., n=14; Control group, n=10. Sheep were around 8-12-months-old. Sheep were randomized with equal groups based on mean weight and sex. Feces were collected two times before treatment and 2-7 days after treatment and just before slaughter. During the study feces were examined for parasite eggs microscopically. Equal numbers of animals (3 from each group) were slaughtered 9, 10, 11 and 12 days after treatment and livers with the bile sack and small intestine contents examined for the presence of parasites. It was concluded that praziquantel at the dose rates used in the study was 95.9% effective against D. dendriticum.

Wydawca

-

Rocznik

Tom

62

Numer

12

Opis fizyczny

p.1381-1382,ref.

Twórcy

autor
  • Istanbul University, 34320, Avcilar, Istanbul, Turkey
autor
autor

Bibliografia

  • 1.Anon.: MAFF. Manual of Veterinary Parasitological Laboratory Techniques. Reference Book 418, HMSO, London 1987.
  • 2.Andrews P., Thomas H., Pohlke R., Seubert J.: Praziquantel. Med. Res. Rev. Bayer Leverkusen, Germany 1983, 3, 147-200.
  • 3.Güralp N., Oðuz T., Zeybek H.: Chemotherapeutic trials with Embay 8440® (Praziquantel, Droncit) against D. dendriticum in naturally infected sheep. Ankara Üniv. Vet. Fak. Derg. 1977, 24, 85-89.
  • 4.Otranto D., Traversa D.: A review of dicrocoeliosis of ruminants including recent advances in the diagnosis and treatment. Vet. Parasitol. 2002, 107, 317-335.
  • 5.Rehbein S., Kokott S., Lindner T.: Evaluation of techniques for the enumeration of Dicrocoelium eggs in sheep faeces. Zntbl. Vet. Med. A 1999, 46, 133-139.
  • 6.Wolff K., Eckert J.: The efficiency of praziquantel against the lancet fluke, Dicrocoelium dendriticumin sheep. Proc. 9th Symp. Scand. Soc. Parasitol. Abo, Finland 1979, p. 54.
  • 7.Wolff K., Hauser B., Wild P.: Dicrocoeliosis of Sheep: Investigation of the Pathogenesis and the Regeneration of the Liver after Therapy. Berl. Münch. Tierärztl. Wschr. 1984, 97, 378-387.
  • 8.Wood I. B., Amaral N. K., Bairden K., Duncan J. L., Kassai T., Malone J. B., Pankavich J. A., Reinecke R. K., Slocombe O., Taylor S. M., Vercruysse J.: World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminant (bovine, ovine, caprine). Vet. Parasitol. 1995, 53, 181-213.

Typ dokumentu

Bibliografia

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Identyfikator YADDA

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