PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2008 | 11 | 3 |

Tytuł artykułu

Azithromycin in the treatment of a dog infected with Giardia intestinalis

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Giardia intestinalis infection is a common cause of diarrhoea in humans and other mammalian species throughout the world. This report describes a case of a dog suffering from diarrhoea, infected with G. intestinalis, effectively treated with azithromycin. Azithromycin is an azalide, semisynthetic macrolide antibiotic having a large spectrum of activity against bacterial pathogens and some protozoa. In this case, Giardia infection in a dog was confirmed by microscopic examination and PCR. Sequencing of the detected Giardia amplicon confirmed infection with assemblage A-I. The dog received azithromycin administered at dose of 10 mg/kg per os, once a day for 5 days. After the therapy, the diarrhoea stopped. Effectiveness of the treatment was also confirmed by PCR and microscopic examination. This is the first report on the therapy of canine giardiosis with azithromycin. It seems that azithromycin can be considered as promising antibiotic for the control of Giardia infection in dogs.

Wydawca

-

Rocznik

Tom

11

Numer

3

Opis fizyczny

p.231-234,fig.,ref.

Twórcy

autor
  • Warsaw Agricultural University, Ciszewskiego 8, 02-786 Warsaw, Poland
autor

Bibliografia

  • Abe N, Kimata I, Iseki M (2003) Identification of genotypes of Giardia intestinalis isolates from dogs in Japan by di­rect sequencing of the PCR amplified glutamate dehyd­rogenase gene. J Vet Med Sei 65: 29-33.
  • Adam RD (2001) Biology of Giardia lamblia. Clin Microbiol Rev 14: 447-475.
  • Barr SC (2006) Giardiasis. In: Greene CE (ed) Infectious Diseases of the Dog and Cat. 3rd ed. Saunders Elsevier, St. Louis, Missouri, pp 736-742.
  • Gardner TB, Hill DR (2001) Treatment of Giardiasis. Clin Microbiol Rev 14: 114-128.
  • Greene CE, Hartmann K, Calpin J (2006) Antimicrobial Drug Formulary. In: Greene CE (ed) Infectious Diseases of the Dog and Cat. 3rd ed. Saunders Elsevier, St. Louis, Missouri, pp 1186-1333.
  • Hoepelman IM, Schneider MME (1995) Azithromycin: the first of the tissue-selective azalides. Int J Antimicrob Agents 5: 145-167.
  • Jeske J, Malinowska B, Kamerys J, Lipowczan G, Olszewska A, Ochecka-Szymanska A (1998) Effectiveness of azi­thromycin in the treatment of giardiasis. Med Sei Monit 4: 547-550.
  • Kateralis PH, Naeem A, Farthing MJG (1994) Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. Aliment Pharmacol Ther 8: 187-192.
  • Taboada J, Lobetti R (2006) Babesiosis. In: Greene CE (ed) Infectious Diseases of the Dog and Cat. 3rd ed. Saunders Elsevier, St. Louis, Missouri, pp 722-736.
  • Zygner W, Jaros D, Skowrońska M, Bogdanowicz-Kamirska M, Wędrychowicz H (2006) Występowanie Giardia intes­tinalis u psów domowych w Warszawie. Wiadomości Parazytologiczne 52: 311-315.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-4d726bc7-f26f-45d3-afca-88afaf01f1bf
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.