Influence of cysteine on mechlorethamine - induced chromosomal aberrations in cultured human lymphocytes

• Autorzy: Blaszczyk A
• Języki publikacji: EN

Abstrakty

EN

The aim of the present paper was to find out by in vitro chromosomal aberration test using human lymphocytes whether cysteine has anticlastogenic properties towards a well-known mutagen - mechlorethamine. The lymphocytes tested were obtained from three healthy donors. Two doses of cysteine (1.0 and 2.0 μg/ml) and three doses of mechlorethamine (0.1,0.2 and 0.3 μg m⁻¹) were tested. It was found that cysteine had anticlastogenic properties and that it reduced the number of metaphases with chromosomal aberrations induced by mechlorethamine.

Słowa kluczowe

EN

cysteine; lymphocyte; human lymphocyte; chromosome aberration; in vitro; mechlorethamine; mutagenicity test

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 1995
• Tom: 36
• Numer: 4
• Opis fizyczny: p.389-393

Twórcy

autor

Blaszczyk A

• University of Lodz, Banacha 12-16, 90-237 Lodz, Poland

Bibliografia

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