Influence of iridovirus on lymphocyte activity: in vitro comparative study in fish

• Autorzy: Siwicki A. , Morand M. , Pozet F. , Bernard D. , Budrewicz B.
• Języki publikacji: EN

Abstrakty

EN

The in vitro effects of iridovirus isolated from catfish on head kidney lymphocyte activity were examined in carp, rainbow trout and sheatfish. Mitogenic proliferative assay was used to demonstrate an immunosuppressive effect of iridovirus on the proliferative response of head kidney lymphocytes stimulated by ConA and LPS. The production of IL-2-like protein by head kidney lymphocytes stimulated by ConA or iridovirus-like agent was also examined in three species of fish. The preliminary in vitro study demonstrated an inhibitory effect of the iridovirus on the proliferative response of head kidney lymphocytes and on the IL-2-like protein production in carp, rainbow trout and sheatfish, but the highest suppressive effect was observed on sheatfish cells. The results suggested that the early-induced iridovirus pathogenicity is the inhibition of the proliferative response and cytokines production by lymphocytes.

Słowa kluczowe

EN

interleukin 2; fish; T lymphocyte; proliferation; lymphocyte activity; in vitro; iridovirus

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2000
• Tom: 03
• Numer: 2
• Opis fizyczny: p.93-96,fig.

Twórcy

autor

Siwicki A.

• University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-719 Olsztyn-Kortowo II, Poland

autor

Morand M.

autor

Pozet F.

autor

Bernard D.

autor

Budrewicz B.