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1993 | 40 | 4 |
Tytuł artykułu

Interactions between the gene products of pma1 encoding plasma membrane H+-ATPase, and pdr1 controlling multiple drug resistance in Saccharomyces cerevisiae

Autorzy
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
In Saccharomyces cerevisiae, the pmal mutations controlling the vanadate resistance of the H+-ATPase activity from the plasma membrane, map on chromosome VII in the vicinity of pdrl mutations controlling multiple drug resistance. However, the pmal-1 mutants exhibit a genotype and a multidrug resistant phenotype quite different from those obtained for pdrl mutants. Quantitative modifications of cycloheximide and N,N'-(p-xylylidene)-bis-aminoguanidine-2HCl resistance are observed in diploids containing the pmal and pdrl genes in trans configuration. Each of the pdrl mutations interacts with pmal as shown by a decrease in the ATPase activity in pdrl/pmal diploids. The in vitro resistance of ATPase activity to vanadate is totally or partially suppressed in pdrl mutants in haploid double mutants. These results suggest that the expression of PMA1 might be controlled by the PDR1 gene product.
Wydawca
-
Rocznik
Tom
40
Numer
4
Opis fizyczny
p.487-496,fig.
Twórcy
  • Wroclaw University, S.Przybyszewskiego 63-77, 51-148 Wroclaw, Poland
Bibliografia
  • 1. Capieaux, E., Ulaszewski, S., Balzi, E. & Goffeau, A. (1991) Physical, transcriptional and genetical mapping of a 24 kb DNA fragment located between the PMA1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae. Yeast 7,275 - 280.
  • 2. Ulaszewski, S., Grenson, M. & Goffeau, A. (1983) Modified plasma membrane ATPase in mutants of Saccharomyces cerevisiae. Eur. ]. Biochem. 130,235 - 239.
  • 3. Balzi, E., Chen, W., Ulaszewski, S., Capieaux, E. & Goffeau, A. (1987) The multidrug resistance gene PDR1 from Saccharomyces cerevisiae. ]. Biol. Chem. 262,16871 - 16879.
  • 4. Rank, G.H. & Bech-Hansen, N.T. (1973) Single nuclear gene inherited cross resistance and col­lateral sensitivity to 17 inhibitors of mitochon­drial function in Saccharomyces cerevisiae. Mol. Gen. Genet. 126,93 - 102.
  • 5. Goffeau, A. & Slayman, C.W. (1981) The proton- translocating ATPase of the fungal plasma membrane. Biochim. Biophys. Acta 639, 197 - 223.
  • 6. Serrano, R. (1988) Structure and function of proton translocating ATPase in plasma mem­branes of plants and fungi. Biochim. Biophys. Acta 947,1 - 28.
  • 7. Ulaszewski, S., Balzi, E. & Goffeau, A. (1987) Genetic and molecular mapping of the pmal mutation conferring vanadate resistance to the plasma membrane ATPase from Saccharomyces cerevisiae. Mol. Gen. Genet. 207,38 - 46.
  • 8. Serrano, R., Kielland-Brandt, M.C. & Fink, G.R. (1986) Yeast plasma membrane ATPase is essen­tial for growth and has homology with (Na+ + K+), K+- and Ca2+-ATPases. Nature (London) 319, 689 - 693.
  • 9. Van Dyck, L., Petretski, J.H., Wolosker, H., Rodrigues, G. Jr., Schlesser, A., Ghisolain, M. & Goffeau, A. (1990) Molecular and biochemical characterization of Dio-9-resistant pmal-1 mutation of the H+-ATPase from Saccharomyces cerevisiae. Eur. J. Biochem. 194,785 - 790.
  • 10. Foury, F. & Goffeau, A. (1975) Stimulation of active uptake of nucleosides and amino acids by cyclic adenosine 3':5'-monophosphate in the yeast Schizosaccharomyces pombe. J. Biol. Chem. 250,2354 - 2362.
  • 11. Ulaszewski, S., Van Herck, J.C., Dufour, J.P., Kulpa, J., Nieuwenhuis, B. & Goffeau, A. (1987) A single mutation confers vanadate resistance to the plasma membrane H+-ATPase from the yeast Schizosaccharomyces pombe. ]. Biol. Chem. 262,223 - 228.
  • 12. Vallejo, C.G. & Serrano, R. (1989) Physiology of mutants with reduced expression of plasma membrane H+-ATPase. Yeast 5,307 - 319.
  • 13. Kotyk, A. & Dvorâkovâ, M. (1992) Are proton symports in yeast directly linked to H+-ATPase acidification. Biochim. Biophys. Acta 1104, 293 - 298.
  • 14. MacCusker, J.H., Perlin, D.S. & Haber,J.E. (1987) Pleiotropic plasma membrane ATPase muta­tions of Saccharomyces cerevisiae. Mol. Cell. Biol. 7, 4082 - 4088.
  • 15. Perlin, D.S., Brown, C.L. & Haber, J. (1988) Membrane potential defect in hygromycin B-re- sistant pmal mutants of Saccharomyces cerevisiae. J. Biol. Chem. 263,18118 - 18122.
  • 16. Hutchinson, D.J. (1965) Studies on cross- -resistance and collateral sensitivity. Cancer Res. 25,1581 -1595.
  • 17. Ling, V., Kartner, R., Sudo, T., Siminovitch, L. & Riordan, J.R. (1983) Multidrug resistance pheno- type in Chinese hamster ovary cells. Cancer Treat. Rep. 67,869 - 874.
  • 18. Curt, G.A., Clendeninn, N.J. & Chabner, B.A. (1984) Drug resistance in cancer. Cancer Treat. Rep. 68,87 - 99.
  • 19. Goldie, J.H. & Coldman, A.J. (1984) The genetic origin of drug resistance in neoplasms: implica­tion for systemic therapy. Cancer Res. 44,3643 - 3653.
  • 20. Rank, G.H., Robertson, A.J. & Phillips, K. (1975) Reduced plasma membrane permeability in a multiple cross-resistant strain of Saccharomyces cerevisiae. }. Bacteriol. 122,359 - 366.
  • 21. Johnston, P.A. & Coddington, A. (1983) Multiple drug resistance in the fission yeast Schizosa­ccharomyces pombe. Correlation between drug and amino acid uptake and membrane ATPase activities. Curr. Genet. 7,299 - 307.
  • 22. Subik, J., Ulaszewski, S. & Goffeau, A. (1986) Genetic mapping of nuclear mucidin resistance mutations in Saccharomyces cerevisiae. Curr. Genet. 10,665 - 670.
  • 23. Ulaszewski, S., Coddington, A. & Goffeau, A. (1986) A new mutation for multiple drug resistance and modified plasma membrane ATPase activity in Schizosaccharomyces pombe. Curr. Genet. 10,359 - 364.
  • 24. Avner, P.R. & Griffiths, D.E. (1973) Studies on energy-linked reactions. Genetic analysis of oligomycin-resistant mutant of Saccharomyces cerevisiae. Eur. J. Biochem. 32,301 - 311.
  • 25. Colson, M., Goffeau, A., Briquet, M., Weigel, P. & Mattoon, J.R. (1974) Nucleo-cytoplasmic in­teraction between oligomycin-resistant muta­tions in Saccharomyces cerevisiae. Mol. Gen. Genet. 135,309-326.
  • 26. Rank, G.H. (1974) Pleiotropy of cytoplasmically and nuclearly inherited resistance to inhibitors of mitochondrial function in Saccharomyces cerevisiae. Can. J. Microbiol. 20,9 -12.
  • 27. Guerineau, M., Słonimski, P. & Avner, P.R. (1974) Yeast episome: oligomycin resistance as­sociated with a small covalently closed non- -mitochondrial circular DNA. Biochem. Biophys. Res. Commun. 61,462 - 469.
  • 28. Nass, G. & Poralla, K. (1976) Genetics of borrelidin resistant mutants of Saccharomyces cerevisiae and properties of their threonyl- -tRNA-synthetase. Mol. Gen. Genet. 147,39 - 43.
  • 29. Rank, G.H., Robertson, A.J. & Phillips, K. (1975) Modification and inheritance of pleiotropic cross resistance and collateral sensitivity in Saccharomyces cerevisiae. Genetics 80, 483 - 493.
  • 30. Rank, G.H. & Sheard, W. (1979) Revertants of pleiotropic cross resistance and collateral sensi­tivity in yeast. A multivariate analysis. Mol. Gen. Genet. 167,309 - 316.
  • 31. Baranowska, H., Polakowska, R. & Putrament,A. (1979) Spontaneous and induced nonspecific drug resistance in Saccharomyces cerevisiae. Acta Microbiol. Polon. 28,181 - 201.
  • 32. Saunders, G.W., Rank, G.H., Kusterman-Kuhn,B. & Hollenberg, C.P. (1979) Inheritance of multiple drug resistance in Saccharomyces cere­visiae: Linkage to leul and analysis of 2(imDNA in partial revertants. Mol. Gen. Genet. 175,45-52.
  • 33. Saunders, G.W. & Rank, G.H. (1982) Allelism of pleiotropic drug resistance in Saccharomyces cere­visiae. Can. J. Genet. Cytol. 24,493 - 503.
  • 34. Falco, S.C. & Dumas, K.S. (1985) Genetic analysis of mutants of Saccharomyces cerevisiae resistant to the herbicide sulfometuron methyl. Genetics 109,21 - 35.
  • 35. Balzi, E. & Goffeau, A. (1991) Multiple or pleiotropic drug resistance in yeast. Biochim. Biophys. Acta 1073,241 - 252.
  • 36. Cohen, J.D. & Eaton, N. (1979) Genetic analysis of multiple drug cross resistance in Saccharo­myces cerevisiae. A nuclear mitochondrial gene interaction. Genetics 91,19 - 33.
  • 37. Meyers, S., Schauer, W., Balzi, E., Wagner, M., Goffeau, A. & Golin, J. (1992) Interaction of the yeast pleiotropic drug resistance genes PDR1 and PDR5. Curr. Genet. 21,431 - 436.
  • 38. Pullman, M.E. & Penefsky, H.S. (1966) Preparation and assay of phosphorylating sub- mitochondrial systems: Mechanically ruptured mitochondria. Meth. Enzymol. 6,277 - 284.
  • 39. Lowry, O.H., Rosebrough, N.J., Farr, A.L. & Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193,265 -275.
  • 40. Witkowska, R., Ulaszewski, S. & Lachowicz, T.M. (1980) N,N'-(p-xylylidene)-bis-aminogua- nidine-2HCl resistant mutants in Saccharomyces cerevisiae and their relation to the amino acid transport system. Acta Microbiol. Polon. 29,57 - 64.
  • 41. Capieaux, E., Vignais, M.L., Sentenac, A. & Goffeau, A. (1989) The yeast H+-ATPase gene is controlled by the promoter binding factor TUF. f. Biol. Chem. 264,7437 - 7446.
  • 42. Schlesser, A., Ulaszewski, S., Ghislain, M. & Goffeau, A. (1988) A second transport ATPase gene in Saccharomyces cerevisiae. ]. Biol. Chem. 263,19480 -19487.
  • 43. Kane, P.M., Yamashiro, C.T. & Stevens, T.H. (1989) Biochemical characterization of the yeast vacuolar H+-ATPase. J. Biol. Chem. 264,19236 - 19244.
Typ dokumentu
Bibliografia
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Identyfikator YADDA
bwmeta1.element.agro-article-468f2b26-3649-424e-b979-d2db651da9c1
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