Metastasis of mammary carcinoma to myocardium in a dog: clinical and morphological correlation

• Autorzy: Nowak M , Noszczyk-Nowak A. , Slawuta P. , Nowaczyk R. , Polanska J.
• Języki publikacji: EN

Abstrakty

EN

A case of a widespread neoplastic process, originating from the mammary gland in mongrel bitch, weighing 27 kg and aging 7 years, was described. In the patient, blood morphology, blood biochemical parameters, gasometry of arterial blood, chest X-ray, and heart ECG and USG were determined. ECG record demonstrated elevation of ST-T segment by 0.2-0.3 mV in I, aVL leads and a downward- sloping depression in III and aVR leads. The alterations pointed with high probability to infarction in the lateral wall of the left ventricle. Following demonstration by imaging tests of numerous tumours in the chest, the dog was subjected to euthanasia. Upon autopsy, apart from the primary tumour in the mammary gland, numerous tumours were demonstrated in inner organs, including myocardium. Histopathology confirmed neoplastic growth of adenocarcinoma type. In the vicinity of the tumour localised in the left cardiac ventricle, microscopic examination disclosed regions of cardiomyocyte necrosis, which corroborated the preliminary diagnosis of infarction.

Słowa kluczowe

EN

mammary adenocarcinoma; mammary carcinoma; cancer; metastasis; myocardial infarction; myocardium; myocardial metastasis; dog; neoplastic process; pathophysiology; mammary gland; skin tumour; morphological correlation

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2007
• Tom: 51
• Numer: 2
• Opis fizyczny: p.313-319,fig.,ref.

Twórcy

autor

Nowak M

• Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland

autor

Noszczyk-Nowak A.

autor

Slawuta P.

autor

Nowaczyk R.

autor

Polanska J.

Bibliografia

• 1. Arnesen K., Gamlem H., Glattre E., Moe L., Nordstoga K.: Registration of canine cancer. Tidsskr Nor Laegeforen 1995, 115, 714-717.
• 2. Benjamin S.A., Lee A.C., Saunders W.J.: Classification and behavior of canine mammary epithelial neoplasms based on life-span observations in beagles. Vet Pathol 1999, 36, 423-436.
• 3. Boldizsar H., Szenci O., Muray T., Csenki J.: Studies on canine mammary tumours. I. Age, seasonal and breed distribution. Acta Vet Hung 1992, 40, 75-87.
• 4. Brodey R.S., Goldschmidt M.H., Roszel J.R.: Canine mammary gland neoplasms. J Am Anim Hosp Assoc 1983, 19, 61-90.
• 5. Destexhe E., Lespagnard L., Degeyter M., Heymann R., Coignoul F.: Immunohistochemical identification of myoepithelial, epithelial, and connective tissue cells in canine mammary tumours. Vet Pathol 1993, 30, 146-154.
• 6. Else R., Hannant D.: Some epidemiological aspects of mammary neoplasia in the bitch. Vet Rec 1979, 104, 296-304.
• 7. Giziński S., Boryczko Z., Katkiewicz M., Bostedt H.: Ki- 67 protein as a prognostic factor in mammary gland tumours in female dogs. Medycyna Wet 2003, 59, 888- 891.
• 8. Haagensen C.D.: Diseases of the breast. Saunders, Philadelphia, 1971, pp. 426-642.
• 9. Jassema J.: Breast cancer. PWN, Warszawa, 1998, pp. 161-168.
• 10. Malicka E., Piusińska W., Endecka H., Bielecki W., Osińska B., Lenartowicz-Kubrat Z.: Neoplasma in dogs on the basis of pathomorphological examinations in the years 1985-1993. Medycyna Wet 1996, 52, 103-106.
• 11. Martin M., Corcoran B.: Diseases of circulatory and respiratory systems in dogs and cats. SIMA WLW, Warszawa, 2000, p. 173.
• 12. Morris J., Dobson J.: Small animal oncology. SIMA WLW, Warszawa, 2003, pp. 188-195.
• 13. Pasławska U., Zyśko D., Gajek J., Noszczyk-Nowak A., Nicpoń J.: Causes and diagnostics of fainting. Medycyna Wet 2005, 61, 253-256
• 14. Perez-Alenza M.D., Tabanera E., Pena L.: Inflammatory mammary carcinoma in dogs: 33 cases (1995-1999) J Am Vet Med Assoc 2001, 219, 1110-1114.
• 15. Ratajska-Michalczak K.: The incidence of mammary gland tumours in the bitch. Medycyna Wet 1980, 36, 168-170.
• 16. Rutteman G.R., Withrow S.J., MacEwen E.G.: Tumors of the mammary gland. In: Small Animal Clinical Oncology. Withrow S.J., MacEwen E.D. (edit), 3rd ed., Philadelphia, 2001, pp. 455-477.
• 17. Szczubiał M., Dąbrowski R., Śmiech A., Łopuszański W., Gawron W., Kusy R., Iwonicki R.: Efficacy of some clinical factors on prognosing the course of malignant mammary tumours in bitches. Medycyna Wet 2004, 60, 160-164.
• 18. Szczubiał M., Łopuszański W.: Prognosis in canine mammary malignant tumours. Medycyna Wet 2002, 58, 261-264.
• 19. Yamagami T., Kobayashi T., Takahashi K., Sugiyama M.: Prognosis for canine malignant mammary tumours based on TNM and histological classification. J Vet Med Sci 1996, 58, 1079-1083.
• 20. Zembrzycka H.. Borkowska E.: The analysis of the occurrence and course of neoplasmatic disease in dogs. Medycyna Wet 1976, 32, 609-612.