EN
Selenium as sodium selenite was injected subcutaneously to rats on day 9 of gestation in single doses of 2.0, 1.0 and 0.5 mg Se/kg or on days 6—15 of gestation in daily dose of 0.5 mg Se/kg. Before term (21 day) dams and fetuses were examined. No evidence of maternal toxicity or teratogenic malformations in any selenium treated group were observed. The reproductive parameters as well as those of fetal development, were found to be better in groups treated with single doses of selenium i.e. 1.0 and 0.5 mg/kg than in controls. Some increase in total number of resorptions was recorded in rats receiving selenium in a dose of 0,5 mg Se/kg from 6th to 15th day of gestation. In this group of animals and in a group given single injection of 2.0 mg Se/kg maternal body weights were lower than those in rats injected with smaller single doses of 1.0 mg Se/kg and 0.5 mg Se/kg.