A dosimetric method of total body irradiation

• Autorzy: Vrtar M
• Języki publikacji: EN

Abstrakty

EN

The determination of the dose delivered to the body during Total Body Irradiation (TBI) is not easy, as direct measurements are impossible. This article presents the intention to develop a systematic and simple method for absorbed dose determination in 60Co TBI using mid plane dose factors (MDF) and external measurements, i.e. entrance and exit dose readings by semiconductor detectors. In order to perform the radiation field analysis prior to TBI treatment, a special silicon n-type detector with increased sensitivity (1200 nC/Gy) was used. The dependence of the calibration factor of this detector exposed to different dose rates in standard and TBI conditions was investigated. A theoretical model of anthropomorphic phantoms of cylindrical ellipsoid shape was established. The software made it possible to generalize the applicability of TBI dosimetry to any individual case of real patient data. A quality assurance analysis of dosimetric results of 350 patients, who underwent TBI during a 17-year period, was performed.

Słowa kluczowe

EN

body irradiation; irradiation procedure; total body irradiation; in vivo; silicon detector; dosimetry

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2002
• Tom: 07
• Numer: 2
• Opis fizyczny: p.337-340,fig.

Twórcy

autor

Vrtar M

• University Hospital Center Rebro, Kispaticeva 12, 10000 Zagreb

Bibliografia

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• 2. Terron, J., Sanchez-Doblado, F., Sanchez-Nieto, B. and Errazquin, L. Midline dose algorithm for in vivo dosimetry. Med. Dosim. 19 (1994), 263-267.
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• 4. Rikner, G. Silicon diodes as detectors in relative dosimetry of photon and electron radiation fields. PhD Thesis, University of Uppsala, 1983.
• 5. Vrtar, M. Model dozimetrije ozračivanja cijeloga tijela pri transplantaciji koštane srži. PhD Thesis, Sveučilište u Zagrebu, 1989.
• 6. Vrtar M. and Purišić, A. Local tissue air ratio in an anatomic phantom for 60Co total body irradiation. Radiother. Oncol. 21 (1991) 157-162.