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2008 | 26 | 2 |

Tytuł artykułu

A relationship between DGAT1 K232A polymorphism and selected reproductive traits in Polish Holstein-Friesian cattle

Warianty tytułu

PL
Zaleznosc miedzy polimorfizmem DGAT1 K232A a wybranymi cechami reprodukcyjnymi bydla rasy polskiej holsztynsko-fryzyjskiej

Języki publikacji

EN

Abstrakty

EN
The aim of the study was to analyse the relationship between DGAT1 K232A polymorphism and bulls’ breeding value for five reproductive traits – age at first insemination, calving-to-conception interval, calving-to-first service interval, non-return rate in heifers, and non-return rate in cows.The investigation was conducted on 264 Polish Black-and-White (Polish Holstein-Friesian) bulls from the active dairy population. DGAT1 genotypes were identified using the PCR-RFLP technique.The K and A allele frequencies were 0.38 and 0.62, respectively. Homozygotes AA were characterized by highest breeding values of non-return rates, both in heifers and in cows. On the contrary, for the age at first insemination and for calving-to-conception and calving-to-first service intervals, the most favourable seemed to be the KK genotype. However, the significant effect of AA (P≤0.01) was obtained only for non-return rate in cows.
PL
Celem pracy była analiza zależności między polimorfizmem DGAT1 K232A a wartością hodowlaną buhajów pod względem pięciu cech reprodukcyjnych – wieku pierwszego unasienienia, okresu międzyciążowego, okresu od ocielenia do pierwszego unasienienia, wskaźnika niepowtarzalności unasieniania jałówek oraz wskaźnika niepowtarzalności unasieniania krów. Badaniem objęto 264 buhaje rasy polskiej holsztyńsko-fryzyjskiej z aktywnej populacji bydła mlecznego. Genotypy DGAT1 identyfikowano metodą PCR-RFLP. Frekwencje alleli K i A wynosiły odpowiednio 0,38 i 0,62. Zwierzęta homozygotyczne pod względem allelu A charakteryzowały się najwyższą wartością hodowlaną wskaźnika niepowtarzalności unasieniania, zarówno jałówek, jak i krów. Natomiast pod względem wieku pierwszego unasienienia i okresów międzyciążowych oraz okresów od ocielenia do pierwszego unasienienia najkorzystniejszy okazał się genotyp KK. Statystycznie istotny (P≤0,01) wpływ genotypu AA udowodniono jednak tylko dla wskaźnika niepowtarzalności unasieniania krów.

Wydawca

-

Rocznik

Tom

26

Numer

2

Opis fizyczny

p.89-95,ref.

Twórcy

autor
  • The August Cieszkowski Agricultural University of Poznan, Wojska Polskiego 71A, 60-625 Poznan, Poland
autor

Bibliografia

  • BENNEWITZ J., REINSCH N., PAUL S., LOOFT C., KAUPE B., WEIMANN C., ERHARDT G.,THALLER G., KÜHN C., SCHWERIN M., THOMSEN H., REINHARDT F., REENTS R., KALM E., 2004 – The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14. Journal of Dairy Science 87, 431-442.
  • BERNAL-SANTOS G., PERFIELD J.W. 2nd., BARBANO D.M., BAUMAN D.E., OVERTON T.R.,2003 – Production responses of dairy cows to dietary supplementation with conjugated linoleic acid (CLA) during the transition period and early lactation. Journal of Dairy Science 86, 3218-3228.
  • BUTLER W., 2003 – Energy balance relationships with follicular development, ovulation and fertility in postpartum dairy cows. Livestock Production Science 83, 211-218.
  • CASTAÑEDA-GUTIÉRREZ E., OVERTON T.R., BUTLER W.R., BAUMAN D.E., 2005 – Dietary supplements of two doses of calcium salts of conjugated linoleic acid during the transition period and early lactation. Journal of Dairy Science 88, 1078-1089.
  • FARESE JR R.V., CASES S., SMITH S.J., 2000 – Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase. Current Opinion in Lipidology 11, 229-234.
  • GAUTIER M., CAPITAN A., FRITZ S., EGGEN A., BOICHARD D., DRUET T., 2007 –Characterization of the DGAT1 K232A and variable number of tandem repeat polymorphisms In French dairy cattle. Journal of Dairy Science 90, 2980-2988.
  • GONG J.G., LEE W.J., GARNSWORTHY P.C., WEBB R., 2002 – Effect of dietary-induced increases in circulating insulin concentrations during the early postpartum period on reproductive function in dairy cows. Reproduction 123, 419-427.
  • GRISART B., COPPIETERS W., FARNIR F., KARIM L., FORD C., BERZI P., CAMBISANO N., MNI M., REID S., SIMON P., SPELMAN R., GEORGES M., SNELL R., 2002 – Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition. Genome Research 12, 222-231.
  • GRISART B., FARNIR F., KARIM L., CAMBISANO N., KIM J.-J., KVASZ A., MNI M., SIMON P.,FRÈRE J.-M., COPPIETERS W., GEORGES M., 2004 – Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. Proceedings of the National Academy of Sciences of the USA 101, 2398-2403.
  • KAUPE B., BRANDT H., PRINZENBERG E.M., ERHARDT G., 2007 – Joint analysis of the influence of CYP11B1 and DGAT1 genetic variation on milk production, somatic cell score,conformation, reproduction, and productive lifespan in German Holstein cattle. Journal of Animal Science 85, 11-21.
  • KAY J.K., MACKLE T.R., BAUMAN D.E., THOMSON N.A., BAUMGARD L.H., 2007 – Effects of a supplement containing trans-10, cis-12 conjugated linoleic acid on bioenergetic and milk production parameters in grazing dairy cows offered ad libitum or restricted pasture. Journal of Dairy Science 90, 721-730.
  • KÜHN C., THALLER G., WINTER A., BININDA-EMONDS O.R., KAUPE B., ERHARDT G.,BENNEWITZ J., SCHWERIN M., FRIES R., 2004 – Evidence for multiple alleles at the DGAT1 locus better explains a quantitative trait locus with major effect on milk fat content in cattle. Genetics 167, 1873-1881.
  • LEROY J.L., VANHOLDER T., MATEUSEN B., CHRISTOPHE A., OPSOMER G., DE KRUIF A.,GENICOT G., VAN SOOM A., 2005 – Non-esterified fatty acids in follicular fluid of dairy cows and their effect on developmental capacity of bovine oocytes in vitro. Reproduction 130, 485-495.
  • LEROY J.L., VANHOLDER T., OPSOMER G., VAN SOOM A., DE KRUIF A., 2006 – The in vitro development of bovine oocytes after maturation in glucose and beta-hydroxybutyrate concentrations associated with negative energy balance in dairy cows. Reproduction in Domestic Animals 41, 119-123.
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  • PERFIELD J.W. 2nd., LOCK A.L., GRIINARI J.M., SAEBØ A., DELMONTE P., DWYER D.A.,BAUMAN D.E., 2007 – Trans-9, cis-11 conjugated linoleic acid reduces milk fat synthesis In lactating dairy cows. Journal of Dairy Science 90, 2211-2218.
  • REIST M., ERDIN D.K., VON EUW D., TSCHÜMPERLIN K.M., LEUENBERGER H., HAMMON H.M., MOREL C., PHILIPONA C., ZBINDEN Y., KÜNZI N., BLUM J.W., 2003 – Postpartum reproductive function: association with energy, metabolic and endocrine status in high yielding dairy cows. Theriogenology 59, 1707-1723.
  • SANDERS K., BENNEWITZ J., REINSCH N., THALLER G., PRINZENBERG E.-M., KÜHN C., KALM E., 2006 – Characterization of the DGAT1 mutations and the CSN1S1 promoter in the German Angeln dairy cattle population. Journal of Dairy Science 89, 3164-3174.
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  • SPELMAN R.J., FORD C.A., MCELHINNEY P., GREGORY G.C., SNELL R.G., 2002 –Characterization of the DGAT1 gene in the New Zealand dairy population. Journal of Dairy Science 85, 3514-3517.
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Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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