EN
Discoloration of the feline iris belongs to the group of anomalies of various etiologies. In diagnosis, nevus pigmentosus, hyperpigmentation, heterochromia iridis and neoplasms have to be considered. Uveal neoplasms include diffuse iris melanoma (DIM) and primary iris and ciliary body melanoma as solid tumors. The paper presents a case of an 11-year-old male Persian cat with histologically diagnosed iris and ciliary body epithelial melanoma. The treatment of choice was enucleation. The morphologically and histologically described melanoma comprised characteristics of both uveal melanoma. The tumor consisted of anaplastic, round, hypopigmented cells with pleomorphic nuclei and prominent nucleoli and balloon-cells with hollow-spheres surrounding nuclei. No spindle-like melanocytes typical for eye primary melanoma were observed. The tumor caused a narrowing filtration angle and secondary glaucoma as well as wide choroid infiltration towards optic nerve papilla and retinal detachment. In the described case no metastasis or local recidivation was discerned.