The flow cytometric analysis of lupin proteins' potential to induce the respiratory burst in human neutrophils

• Autorzy: Klos P. , Poniedzialek B. , Lampart-Szczapa E. , Gralik J. , Wiktorowicz K.

Warianty tytułu

PL

Cytometryczna analiza potencjalu bialek lubinu do stymulowania wybuchu oddechowego w neutrofilach czlowieka

• Języki publikacji: EN

Abstrakty

EN

There is an everincreasing demand for lupin seed protein in human nutrition. However, their usage as a food ingredient can be limited by their influence on the immune system. The aim of the study was to analyse, by means of flow cytometry, the potential of lupin seed globulins to induce the respiratory burst in human neutrophils. The results proved the potential of lupin globulins to induce the increased ROS production in human neutrophils. The increased ROS production by the cells treated with lupin globulins and, at the same time, stimulated with the PMA may suggest a synergistic effect of the globulins and the PMA.

PL

Białka z nasion łubinu znajdują coraz większe zastosowanie w żywieniu człowieka. Ich wykorzystanie jako składnika żywności może być jednak ograniczone wpływem tych białek na układ immunologiczny. Celem badania było przeanalizowanie, za pomocą cytometrii przepływowej, potencjału globulin z nasion łubinu do indukowania wybuchu oddechowego w neutrofilach człowieka. Uzyskane wyniki dowiodły zdolności globulin łubinu do stymulowania zwiększonej produkcji reaktywnych form tlenu przez ludzkie neutrofile. Zwiększone generowanie ROS przez komórki poddane działaniu globulin łubinu i jednocześnie stymulowane PMA może sugerować synergistyczne działanie globulin w stosunku do PMA

• Wydawca: -
• Czasopismo: Acta Scientiarum Polonorum. Technologia Alimentaria
• Rocznik: 2009
• Tom: 08
• Numer: 1
• Opis fizyczny: p.91-97,fig.,ref.

Twórcy

autor

Klos P.

• Poznan University of Life Sciences, Poznan, Poland

autor

Poniedzialek B.

autor

Lampart-Szczapa E.

autor

Gralik J.

autor

Wiktorowicz K.

Bibliografia

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