Wystepowanie genow bialek adhezyjnych u szczepow Staphylococcus aureus nie wytwarzajacych koagulazy

• Autorzy: Wisniewska K. , Garbacz K. , Piechowicz L.

Warianty tytułu

EN

Occurrence of adhesin genes in coagulase-negative Staphylococcus aureus strains

• Języki publikacji: PL

Abstrakty

PL

U 57% koagulazo-ujemnych szczepów S. aureus wykryto 4 z 6 genów białek adhezyjnych: fnbB, fib, cna i clfA. U wszystkich szczepów występował gen czynnika zlepnego CF (clfA), u 90% gen białka wiążącego fibrynogen (fnbB) także u 90% gen białka wiążącego fibrynę (fib), a u 67% gen białka wiążącego kolagen (cna). Poszczególne geny częściej występowały u szczepów MRSA niż MSSA.

EN

Sixty fenotypically coagulase-negative Staphylococcus aureus strains were screened for the presence of six adhesion genes. The strains were isolated from varied clinical samples and varied patients in 16 medical centers, in majority from the region of Gdansk. Multiplex PCR in two primer sets was used for detection of the following genes: bbp (bone binding protein), cna (collagen binding protein), ebp (elastin binding protein) and fhbB (fibronectin В binding protein), fib (fibrinogen bindng protein) and clfA (clumping factor A). More than half (57%) of the examined population harbored four genes: fnbB, fib, cna і clfA. All of the strains were found to be clfA positive and 90% of them were positive for fnbB, 90% for fib and 67% for cna. All of these genes were significantly more common in MRSA than in MSSA. The particular genes were occurred in strains derived from varied clinical samples.

Słowa kluczowe

PL

szczepy bakteryjne; Staphylococcus aureus; bialka adhezyjne; bialko cna; bialko clfA; bialko fnbB; bialko fib; koagulaza; diagnostyka mikrobiologiczna; fibryny; kolagen; fibrynogen; fibronektyna; elastyna

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2006
• Tom: 58
• Numer: 2
• Opis fizyczny: s.113-117,tab.,bibliogr.

Twórcy

autor

Wisniewska K.

• Akademia Medyczna w Gdansku, ul.Do Studzienki 38, 80-227 Gdansk

autor

Garbacz K.

autor

Piechowicz L.

Bibliografia

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