Badania transmisji szczepow Haemophilus influenzae typu b krazacych w populacji dzieci w przedszkolach i domach dziecka

• Autorzy: Augustynowicz E. , Nowaczek A. , Szenborn L. , Banys D. , Gzyl A. , Dabrowski W. , Samet A. , Slusarczyk J.

Warianty tytułu

EN

Haemophilus influenzae type b strains transmission among children attending day-care canters and orphanages

• Języki publikacji: PL

Abstrakty

PL

Szczepy H. influenzae wytwarzające otoczkę polisacharydową, odmiennie do szczepów bezotoczkowych stanowią zwartą klonalnie grupę. Celem pracy było określenie poziomu zmienności szczepów H. influenzae typu b izolowanych od zdrowych dzieci z przedszkoli oraz domów dziecka oraz szczepów izolowanych z zakażeń inwazyjnych. W pracy oceniono przydatność metody PFGE w badaniach transmisji szczepów Hib krążących w populacji oraz dochodzeniach epidemiologicznych w obrębie trzech wykrytych ognisk zakażenia inwazyjnego szczepami Hib.

EN

Goal of the work was to evaluate the differences level among H. influenzae strains of b serotype isolated from children attending day-care centres and orphanages and among strains isolated from invasive infections. In the work PFGE in Hib strains transmission examination and for epidemiological studies among three sources of invasive infection was applied. Among 35 Hib strains tested and control strain 8 different pulsotyped were found. Among 21 strains colonising the nasopharynx of healthy children, and among 13 Hib strains isolated from cerebrospinal fluid, 6 and 1 pulsotypes were fund, respectively. Results obtained show that healthy children might be colonizing with genotypes characteristic for Hib strains isolated from invasive infections. In this view wider Hib vaccination seems be expected, as Hib circulation is common.

Słowa kluczowe

PL

choroby czlowieka; infekcja bakteryjna; dzieci; domy dziecka; przedszkola; szczepy bakteryjne; drogi oddechowe; transmisja; Haemophilus influenzae; metoda PFGE; epidemiologia

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2005
• Tom: 57
• Numer: 1
• Opis fizyczny: s.39-49,rys.,tab.,bibliogr.

Twórcy

autor

Augustynowicz E.

• Panstwowy Zaklad Higieny w Warszawie, ul.Chocimska 24, 00-791 Warszawa

autor

Nowaczek A.

autor

Szenborn L.

autor

Banys D.

autor

Gzyl A.

autor

Dabrowski W.

autor

Samet A.

autor

Slusarczyk J.

Bibliografia

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