EN
Subcutaneous injection of Ascaris lumbricoides suis homogenate in guinea pigs causes a significant increase of "neutral" spleen homogenate proteases, as well as of the activity of the splenic and renal post- nuclear fraction in days 2 or 3. Also, in experimental larval ascariasis in guinea pigs, a rise of proteolytic activity in the post-nuclear spleen fraction is observed 7 to 8 days after infection. The activity of "neutral" lung proteases in animals receiving Ascaris homogenate shows only tendency to increase. The proteolytic activity of liver, kidneys and heart preparations did not reveal significant differences in guinea pigs after Ascaris homogenate administration, nor in experimental larval ascariasis.