Duze zwierzeta modelem niewydolnosci serca

• Autorzy: Noszczyk-Nowak A , Jankowska E. , Paslawska U. , Janiszewski A. , Kiczak L. , Bania J. , Tomaszek A. , Zacharski M. , Nicpon J. , Ugorski M. , Ponikowski P. , Banasiak W.

Warianty tytułu

EN

Large animal models of heart failure

• Języki publikacji: PL

Abstrakty

EN

Congestive heart failure is a clinical syndrome whose hallmarks are fatigue and dyspnea. Common pathophysiologic features of heart failure include changes in the structure of the left ventricle of the heart, function, and neurohormonal activation. A recapitulation of the heart failure phenotype in a large animal model can make it possible to translate basic science discoveries into clinical therapies. Models of myocardial infarction/ischemia, ischemic cardiomyopatyhy, ventricular pressure and volume overload and pacing- -induced dilated cardiomyopathy have been created for dogs, pigs and sheep to investigate heart failure and potential therapies. This article presents types of large animal models of heart failure, methods of their development and their clinical usefulness.

Słowa kluczowe

PL

choroby serca; niewydolnosc serca; niedokrwienie miesnia sercowego; kardiomiopatie; modele zwierzece; owce; psy; swinia

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2010
• Tom: 66
• Numer: 06
• Opis fizyczny: s.378-382,rys.,tab.,bibliogr.

Twórcy

autor

Noszczyk-Nowak A

• Wojewodzki Szpital Specjalistyczny Osrodek Badawczo-Rozwojowy, ul.Kaminskiego 73a, 51-124 Wroclaw

autor

Jankowska E.

autor

Paslawska U.

autor

Janiszewski A.

autor

Kiczak L.

autor

Bania J.

autor

Tomaszek A.

autor

Zacharski M.

autor

Nicpon J.

autor

Ugorski M.

autor

Ponikowski P.

autor

Banasiak W.

Bibliografia

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